List of Biotech, Pharmaceutical & Life Sciences companies in Ohio - 93

3BarBio offers increased profitability to discovery companies, bulk suppliers, and distributors by addressing the major hurdle to further adoption of biologics by designing innovative packaging to deliver viable microbes to the ag market. With its proprietary LiveMicrobe® Design. Develop. Deliver. process, 3Bar delivers on demand for partners around the world.

Founded in 2006, Affinity Biosciences is a pioneering Life Science and High-Tech company whose biochemical products and services are mainly applied in biotechnology, medical research and pharmaceutical development. Dedicating to advancing customer success through innovation, Affinity Biosciences has established R&D affiliates in the United Kingdom and United States with the aim of providing outstanding service around the globe.Our customers include scientists and technologists in life science companies, university and government institutions, hospitals and industry. To underline our commitment to our customers and enhance our standards of service, we have opened packaging and quality control facilities in the People’s Republic of China. Our goal is to develop high-quality antibody that focuses on Cell Signaling Transduction research, including Akt,AMPK,NF-KappaB,TGF-beta,etc,as well as inhibitors and related reagents.

Created in 2011 as a spin-out of Cincinnati Children's Hospital Medical Center (CCHMC), Airway Therapeutics has extensive expertise in protein development for applications in the lungs and pediatrics. Airway Therapeutics is in advanced preclinical phase of developing AT-100 (rhSP-D), a product targeting bronchopulmonary dysplasia (BPD) in newborns.

Akrotome Imaging, Inc. is focused on the clinical translation of cancer-targeted molecular probes into enhanced approaches for surgery and diagnostics, leading to improved outcomes and patient quality of life while positively impacting healthcare economics. Akrotome is a Delaware C Corporation with offices in Ohio, Indiana, and California. The company was first incorporated in 2008 and the current management team has been in place since May of 2012. The company's approach stresses the efficient use of capital, coupled with strategies that emphasize the fastest routes to the clinical market with the lowest regulatory overhead.

Allinaire is developing humanized anti-endothelial monocyte activating polypeptide II (EMAP II) monoclonal antibodies, which are currently being progressed as a potential disease-modifying treatment for PAH. Allinaire was founded in 2016 by BioMotiv (www.biomotiv.com; now managed by Advent Life Sciences, www.adventls.com), with the licensed technology from Indiana University. EMAP II is a non-classical cytokine which impacts apoptosis, cell injury, endothelial cell function and inflammation. Based on the pioneering work by the scientific founders, Matthias Clauss, PhD and Irina Petrache, MD, and their colleagues at Indiana University and National Jewish Health, Allinaire Therapeutics and their network of preclinical and clinical scientists, have demonstrated a pivotal pathogenic role of EMAP II in cardiopulmonary diseases, including pulmonary arterial hypertension (PAH), chronic obstructive pulmonary disease (COPD), and viral-induced acute lung injury.

American Dermatopathology Laboratory is the creative vision of Dr. H. Nicholas Shamma. They are a comprehensive, CLIA certified and independent laboratory, with a nationwide reach. As a physician owned lab focused on providing clinicians and their patients with reliable diagnoses of skin biopsies, they use state of the art processes and a high standard of care.

Founded in 1996 in Cleveland, OH, Analiza, Inc. is a leading US based provider of high quality, affordable analytical services for physicochemical and ADME properties for early drug discovery markets. Adapting gold standard methods for compatibility with early drug discovery (throughput, sample requirements, turnaround time, and cost), Analiza developed the first automated, miniaturized, shake flask system for LogD in 1999. Since 2005, Analiza has provided over 150,000 solubility measurements, 45,000 LogD measurements and 2,500 pKa measurements. Analiza extends the in-house physchem and ADME profiling capabilities of small and large pharma and biotech alike.

Andelyn Biosciences is a gene therapy CDMO dedicated to Turning Hope into Reality™. Our capabilities span viral vector process and analytical development, adherent and suspension based GMP drug substance manufacturing up to 2,000L, as well as GMP plasmid process development and GMP manufacturing. We are located in Columbus, OH, USA. With more than 20 years of pioneering experience in viral vector and vaccine manufacturing, Andelyn offers its clients direct access to globally recognized thought leaders with extensive expertise. We have produced GMP material for over 75 worldwide clinical trials in addition to over 450 cGMP clinical batches and more than 2,000 research-grade productions. Andelyn provides research and tox grade plasmids with an additional offering of GMP plasmid manufacturing, advanced quality systems, full regulatory support, semi-automated to automated fill stations, and supply chain vertical integration. Our 180,000 sq ft clinical and commercial manufacturing facility comprises 16 upstream production suites for customization of new and tech transferred programs. Andelyn offers clinical through commercial-scale capabilities that will help accelerate the development and manufacturing of innovative therapies to bring more treatments to more patients.

Armatus Bio is a biotechnology company that specializes in precision gene therapy for raising expectations in FSHD.

Athersys is a clinical stage biopharmaceutical company with a growing pipeline of highly differentiated, potential best in class therapeutics to treat significant and life-threatening diseases. We are engaged in the discovery and development of innovative new medicines designed to extend and enhance the quality of human life. Through the application of our proprietary technologies, we have established a pipeline of therapeutic product development programs in multiple disease areas. This pipeline includes both stem cell therapy and pharmaceuticals.

Founded in 1987, ATL, A Bureau Veritas Company, is a Scientific Sourcing Solutions Company. For more than 30 years, we’ve exceeded the highest expectations of the world’s most demanding customers in the Consumer Products, Pharmaceutical and Medical Device industries. ATL, A Bureau Veritas Company, has become a recognized leader in creating innovative sourcing solutions across the entire product life cycle, from discovery through commercialization. Our services range from standard rules-based testing to operating and managing entire scientific functions. We’re experts in the field of scientific sourcing. Across all levels of complexity, oversight and location, we transform cost-saving measures into strategic solutions. We can elevate your existing proficiencies and resources — all while protecting the critical continuity of business, knowledge and talent. Our capabilities include: Analytical Chemistry, Engineering, Life Science, Product Performance Testing, Product Safety and Regulatory, and Quality Assurance. At ATL, A Bureau Veritas Company, our unique solutions help maximize readiness, efficiency and productivity for our clients. We are committed to continue making “exceptional our ordinary” while delivering the science that makes life better. Careers At ATL, A Bureau Veritas Company, we don’t just do the science, we have the opportunity to transform organizations. We need people who want to grow with us and contribute directly to our clients’ success. As scientific sourcing experts, the largest and most respected companies in the world ask us to create innovative solutions to big problems. We have more input and influence, so we can have a significant impact on brand-name products and visible projects. And you can play a bigger role.

Atreon Orthopedics is a tissue regeneration company powered by breakthrough regenerative technology and renowned scientific expertise. Tendon and ligament injuries affect ten million people yearly, spanning all lifestyles and demographics. Atreon is committed to dramatically improving healing and long-term outcomes for patients encountering these soft-tissue injuries. ROTIUM®, our initial product for rotator cuff repair, is a bioresorbable wick designed as a scaffold to harness and hold biologically active substances at the repair site providing a pro-healing environment that promotes healthy tissue and native tissue regeneration. Recently published human and animal studies and over 10,000 cases have shown a safe and effective solution to improving biology, restoring function, and improving rotator cuff success rates.

AtriCure, Inc. provides innovative technologies for the treatment of Afib and related conditions. Afib affects more than 37 million people worldwide. Electrophysiologists, cardiothoracic and thoracic surgeons around the globe use AtriCure technologies for the treatment of Afib, reduction of Afib related complications and post-operative pain management. AtriCure's Isolator® Synergy™ Ablation System is the first medical device to receive FDA approval for the treatment of persistent Afib. AtriCure's AtriClip® Left Atrial Appendage Exclusion System products are the most widely sold LAA management devices worldwide. AtriCure's Hybrid AF™ Therapy is a minimally invasive procedure that provides a lasting solution for long-standing persistent Afib patients. AtriCure's cryoICE cryoSPHERE®+ and cryoSPHERE MAX™ probes are cleared for temporary ablation of peripheral nerves to block pain, providing pain relief in cardiac and thoracic procedures. For more information, visit AtriCure.com or follow us on X (formerly Twitter) @AtriCure.

Auxilium Health is developing low-cost and smart biomaterials for hard-to-heal wounds. Our mission is to empower patients to take control of their healing journey by providing technology that actively heals and monitors wound infections, enabling faster recovery times and better quality of life for patients. We are providing a smarter way to heal wounds, one patient at a time.

Avantor® is a leading global provider of mission-critical products and services to customers in the biopharma, healthcare, education & government, and advanced technologies & applied materials industries. Our portfolio is used in virtually every stage of the most important research, development and production activities in the industries we serve. Our global footprint enables us to serve more than 300,000 customer locations and gives us extensive access to research laboratories and scientists in more than 180 countries. We set science in motion to create a better world. More than 14,500 strong, our associates are passionate about our mission to set science in motion to create a better world. We share enthusiasm for innovation, excellence, and achievement. Whether we are collaborating with our customers to advance science or solve multifaceted problems, we help them reach their goals more efficiently and effectively. Visit our website to learn more about Avantor.

AxioMed was founded to advance the standard of care for patients with degenerative spine conditions by progressing spine technology beyond fusion and first-generation artificial discs. We passionately believe that next-generation lumbar and cervical total disc replacement (TDR) technology will transform the lives of patients on a global scale. Led by an experienced surgeon team utilizing patented viscoelastic polymer technology, AxioMed is developing the next generation of artificial discs. Our Vision: Focusing on restoration of the natural function of the spine, AxioMed will enhance human health through research, innovation, development and service world-wide. AxioMed LLC is a KICVentures company. For all AxioMed jobs visit: http://www.kicventures.com/blog/careers/

Basking is developing the first in class agent (BB-031) targeting von Willebrand Factor (VWF) along with a direct acting reversal agent (BB-025) to immediately the pharmacological effect of BB-031 in the event of bleeding. BB-031 is an RNA aptamer optimized for rapid onset of action and short duration of effect. Basking will initiate a Phase 2 trial in acute ischemic stroke in late 2023 and is exploring further application in pulmonary embolism in preclinical studies. The technology is based on two decades of translational research on RNA aptamers as therapeutic agents for cardiovascular diseases.

BioHeights LLC specializes in business strategy for novel cell and gene therapies. We help companies, startups, and academic institutions.

BIOHM optimizes digestive health by combining good bacteria, good fungi and enzymes to break down digestive plaque, allowing for total gut balance. This allows BIOHM's 30 billion live active cultures to maintain, support, and promote the balance of the total microbiome in the digestive system.

Case Western Reserve University is a Higher Education institution that offers research and academic programs.

Celloram Inc. is a preclinical stage company founded in 2018. Our team of experienced leaders and scientists share a passion for improving the health and well-being of patients and families affected by cancer and chronic disease. Celloram has a deep sense of social responsibility. We are dedicated to the community in which we reside and work, and where we honor our commitment to promote diversity by inspiring, educating and developing the next generation of scientists and leaders. Celloram now leverages its key discoveries to develop unique forms of cell therapy and small molecule therapeutics that harness our body’s own unique potential to heal and battle chronic illnesses including cancer, autoimmune disease, chronic inflammatory and metabolic disorders. Our mission and vision stem from our strong belief in the potential of new, less toxic therapies with the power to ignite our body’s self-healing process. With an ideal location at University Circle, Cleveland, OH, Celloram has benefited greatly from partnerships with health care leaders at two of the nation’s leading academic medical centers, including Case Western Reserve University School of Medicine and University Hospitals Cleveland Medical Center. Supported by a highly motivated and dedicated group of partners and investors, Celloram has developed a pipeline of four unique therapeutics: Sopprimerex, Protexi, NOVS-100, and CLM-022. These cutting-edge therapies are in distinct phases of preclinical development and are rapidly advancing through essential steps that will position each core asset for entry into clinical trials and evaluation by the FDA. Our team at Celloram is committed to sharing our discoveries and advancing them for the benefit of human health.

Cellular Technology Limited (CTL) has been pioneering the ELISPOT technology for immune monitoring. For nearly 20 years, CTL's mission has been "Elevating ELISPOT to an Exact Science". Serving over 2,000 clients from academia and industry worldwide, CTL offers unparalleled expertise in immune monitoring. We offer: Contract Laboratory: Immune monitoring with an emphasis on T and B cells in a CLIA-certified, GLP-compliant laboratory with processing capabilities of up to 450 samples per week. Assays include: ELISPOT, ELISA, FACS, CBA, Proliferation, and more. Comprehensive solutions for sample processing: Whole blood processing with optimized PBMC cryopreservation methods that ensure good cell functionality. All-around ELISPOT including: – Protocols and reagents for human PBMC cryopreservation, processing, and testing – Human PBMC reference samples as reference standards for assay performance. – Extensive Cryopreserved PBMC Library: The largest commercially available library of donors available both uncharacterized and with established T cell reactivity. – ImmunoSpot® Kits: Standardized T Cell and B Cell ELISPOT Kits. Single- and Double-color Enzymatic ELISPOT. Up to Four-color T Cell & B Cell FluoroSpot Kits. Cytokine/Antibody combination multicolor FluoroSpot Kits. – Non-radioactive human Natural Killer/ADCC Assessment Kits – Positive and negative control antigens. – Consultation and Hands-on Workshop Training on the use of ELISPOT for immune monitoring. – ImmunoSpot® Analyzers for automated and objective ELISPOT data analysis and streamlined data processing with audit trails. – BioSpot® Analyzers for serum antibody neutralization tests; Viral Plaque, PRNT, Viral ICA, Serum Neutralization Assays, and Serum Bactericidal Assays, all with multicolor capability. – Serum-free Media for washing, testing, and freezing PBMC – Plate Scanning and Analysis Services

Cell X is pioneering a revolution in cell processing. At the core of this revolution lies our transformative Celligent platform – an innovative bundling of automation, imaging, data analytics, and machine learning that enables therapeutic researchers to develop consistent, reproducible, and scalable GMP-compliant processes for stem cells and bio-fabrication. Celligent enables the development of safe and effective products by executing the necessary process development and cell manufacturing procedures in a fully documented, compliant way. Successful cellular therapies demand starting with optimized cell sources; and intrinsic variability and heterogeneity among cell sources presents a major challenge. This critical first step of control over starting materials demands the use of quantitative and reproducible standards for cell and clone selection and process management based on critical process parameters (CPPs) in order to achieve products with defined critical quality attributes (CQAs). Backed by a highly experienced team, Cell X automates cell processing in diverse cell culture applications spanning mesenchymal stromal/stem cells (MSCs) and exosomes, induced pluripotent stem cells (iPSCs), hematopoietic stem cells (HSCs), connective tissue progenitor cells (CTPs) and tumor-infiltrating lymphocytes (TILs) as well as other progenitor cell types. We are dedicated to advancing the promise of cellular therapies for innovators and patients alike, ultimately making cell therapies more accessible to millions of patients worldwide. 

CeutiCare improves outcomes and lowers medical costs of treating the chronically ill patient. CeutiCare's Intelligent Clinical Guidance (ICG) system provides knowledge-based technology to support evaluation of patients by a pharmacist or other physician extender at the patient's point of care. Our proprietary ICG system evaluates patient clinical data and recommends patient-specific, evidence-based medication therapy to help the patient get better and feel well.

Cincinnati Children's, a nonprofit academic medical center established in 1883, offers services from well-child care to treatment for the most rare and complex conditions. It is the Department of Pediatrics at the University of Cincinnati College of Medicine and trains more than 600 residents and clinical fellows each year. Cincinnati Children's is a force in pediatric research and offers some of the best research-based education and training programs in the nation. We are proud to be an Equal Opportunity Employer that values and treasures Diversity, Equity, and Inclusion. We are committed to creating an environment of dignity and respect for all our employees, patients, and families (EEO/AA).

CinRx Pharma is a biotech company advancing a diverse portfolio of high-impact medicines through clinical development with a unique hub-and-spoke business model. CinRx’s approach combines financing with the efficient progression of therapeutic candidates within its portfolio, each managed by CinRx’s central infrastructure and operating team. Current CinCos address areas of high unmet medical need including metabolic, gastrointestinal, and oncology. Differentiated by an asset selection process agnostic to therapeutic area, a strategic CRO partnership, and insights from thousands of development programs, CinRx identifies, funds and accelerates promising drugs with the potential to have the highest impact on patients’ quality of life. CinRx Pharma is headquartered in Cincinnati, Ohio.

Clarametyx Biosciences Inc. is a clinical stage biotechnology company developing immune-enabling biologic therapies to fight life-threatening infections. Our novel technology platform targets the protective barrier around bacteria, known as biofilms.

Cleveland Clinic, located in Cleveland, Ohio, is a not-for-profit, multispecialty academic medical center that integrates clinical and hospital care with research and education. Founded in 1921 by four renowned physicians with a vision of providing outstanding patient care based upon the principles of cooperation, compassion and innovation, Cleveland Clinic has become one of the largest and most respected hospitals in the country. Cleveland Clinic facilities can be found throughout Northeast Ohio, as well as around the country and world including: Cleveland Clinic Florida Cleveland Clinic Canada Cleveland Clinic Abu Dhabi Cleveland Clinic Lou Ruvo Center for Brain Health - Las Vegas Cleveland Clinic health system includes eight regional hospitals, 16 family health centers, a children's hospital for rehabilitation and one affiliate hospital. Cleveland Clinic is accredited by The Joint Commission, the nation’s largest accreditor of healthcare organizations. Our family health centers offer: Outpatient care Primary care Numerous subspecialties Numerous locations All of our hospitals, family health centers, outpatient clinics and home healthcare programs are also accredited by The Joint Commission under its hospital accreditation program.

One of the few FDA-licensed cord blood centers in the U.S., the Cleveland Cord Blood Center (CCBC) collects, processes, stores and distributes stem-cell rich umbilical cord blood for transplantation in patients with life-threatening disorders.

Cleveland Diagnostics is developing a breakthrough technology to discover a new class of diagnostics tests with high sensitivity and specificity for many cancers – early on, when cancer is still curable.

CollaMedix develops medical devices that are based on collagen. These devices are made using electrocompaction technology. Electrocompacted collagen devices can enhance soft tissue repair and augmentation. One example is CollaFabric®, a load-bearing fabric made from collagen.

Patented, Drug-Free, Faster, and More Effective Treatment for Vaginal Infections. Powered by Project Medtech.

DAPCEL, Inc. is a research biotechnology company focused on the development of strategies for optimization of enhanced protein production in any desired host organism. To this end DAPCEL, Inc. utilizes unique Two-Layered DAPCEL™ RC (Rare Codon) Gene Optimization approach for gene redesign.

Deep Lens is a digital healthcare company focused on enabling faster recruitment of the best-suited cancer patients for clinical trials at the time of diagnosis using VIPER. Deep Lens' AI-driven cloud platform gives care teams, trial coordinators and oncologists visibility into all available trials and the ability to collaborate on groundbreaking cancer research across all cancer types.

Diasome Pharmaceuticals, Inc. is a clinical-stage biopharmaceutical company pioneering hepatocyte cell targeting to restore hepatocyte metabolism and treat metabolic diseases. Restoring hepatocyte function addresses the root dysregulations in common metabolic diseases like diabetes, obesity, and dyslipidemia. Our therapies leverage the Hepatocyte's natural regulatory functions, aiming to deliver superior patient outcomes and improved disease management.

DNA Diagnostics Center is a biotechnology company that specializes in paternity DNA testing and forensic DNA analysis.

Eikonoklastes Therapeutics is an early stage biopharmaceutical company focused on rapidly advancing innovative medicines for numerous areas of significant unmet clinical need, starting with neurodegenerative diseases. We are iconoclasts who are passionate about finding new and better ways to treat disease. Our first-in-class gene therapy moves beyond single defective gene replacement. It is a transformational, disease-modifying gene supplement therapy with a unique mechanism of action that provides extra copies of a critical gene to cause overexpression of a critical neurotrophic factor that is essential for neuromuscular signaling and function. Our initial focus is on Amyotrophic Lateral Sclerosis (ALS, Lou Gehrig’s Disease), a rare, yet debilitating nerve disease that causes progressive muscle degeneration and eventual death. An estimated 5,000 new patients in the U.S. are diagnosed each year with ALS, and there are few treatment options beyond supportive care. Our dynamic discovery and development approach allows us to focus on accelerated approvals and outsized returns for ALS and potentially other neurodegenerative diseases such as Parkinson’s, Huntington’s, Alzheimer’s, traumatic brain injury, and more.

Enspire DBS Therapy, in partnership with Cleveland Clinic and Boston Scientific, is developing a proprietary deep brain stimulation (DBS) therapy to restore motor function for stroke survivors living with disability. Enspire is currently sponsoring EDEN, a Phase I clinical trial of DBS therapy for stroke recovery.

We are a specialty CDMO for LV vector manufacture & use. Our three platforms: Expression Cassette Optimization (ECO), LentET (3rd gen system), & LentET Express (cGMP mfg.) enable GMP LV manufacture 10 months from sequence submittal. ECO increases expression up to 8 fold. LentET plasmids are ECO optimized, have improved safety, produce potent LVs & may be available royalty/licensing free depending upon the specifics. With full CMC & regulatory support, Expression is your preferred CDMO of choice.

Farmed Materials is working to create a novel source of natural rubber by commercializing Taraxacum kok-saghyz, the Kazakh dandelion or TK – a specialty crop that can be cultivated throughout a large global geography and which produces high-quality natural rubber and other beneficial sugars, proteins and ligands.

Forge is a gene therapy development engine, focused on enabling access to life changing gene therapies and helping bring them from idea into reality. We partner with innovators in the gene therapy community: scientists, physicians, biotech/pharma companies, and patient groups. We bring expertise in gene therapy manufacturing and therapeutics development to the table, helping champion teams that are navigating the long road from the lab bench to the bedside. With a patients-first approach, we are forging new models for working together to better accelerate these transformative medicines to reach those who need them most.

Frantz Viral Therapeutics is focused on the development of topical treatments for pre-cancerous conditions related to human papillomavirus (HPV) infections in the cervix, vulva, and anus.

Genetesis is a rapidly growing medical imaging company leveraging data science and biomagnetism in the fight against cardiovascular disease.

GenomOncology enables real-time clinical decision-making at the point-of-care for Molecular Pathologists, Clinical Oncologists and Cancer Informaticists in their research of cancer treatments and therapies for cancer patients.

Genosera is revolutionizing the gene therapy field with its next generation gene therapy treatments that can help stop the progression of diseases and allow patients to regain their health. Founded in 2019, Genosera is a privately held, gene therapy biotechnology company located in Columbus, Ohio.

Gnome Sciences is a U.S.-based, CLIA-certified CRO that specializes in complex histopathology and molecular biology studies. We take pride in our unique capability to undertake challenging projects – the types of studies that larger companies often shy away from and that smaller organizations cannot handle. Our expertise ranges from multiplex IHC/ISH to gene expression analysis, but the thing that really sets Gnome apart is that we love the science and care about your project as much as you do

Haima Therapeutics is a pre-clinical stage biotechnology company focused on developing bio-inspired therapies for the treatment of bleeding and other blood-related ailments. We have developed a novel, nanoparticle-based synthetic hemostatic technology, called SynthoPlate, that can staunch hemorrhagic bleeding by binding to the site of injury and amplifying your body’s natural clotting mechanisms. Haima Therapeutics and Case Western Reserve University entered into an option to license agreement in April of 2018. Haima Therapeutics is located at the BioEnterprise incubator centrally located in the University Circle area near Case Western Reserve University, University Hospitals, and the Cleveland Clinic.

Heidelberg University is a higher education institution offering a variety of academic programs and research opportunities.

✨ Journey Biosciences is on a mission to shift the future of care. 🧬 Our flagship solution blends the precision of NaviDKD®, a clinically-validated predictive screening, with the AI-driven insights of Compass™, to offer up to 12 years of advanced diabetes-related kidney disease (DKD) detection, plus tailored intervention strategies to slow or prevent progression. 🎯 This approach improves patient outcomes, optimizes resource allocation, and reduces costs. 🔍 Discover more about our transformative approach at journeybio.life.

Lab-Ally is a company that specializes in providing ELN and LIMS Software for GLP labs, universities, and institutions, as well as offering various services related to biospecimens, histopathology, and sales and marketing for biotechnology and scientific research companies.

LexaMed is a company dedicated to providing the pharmaceutical, medical device and biotechnology industries with quality, compliant, state-of-the-art services in the areas of consulting, auditing, and laboratory testing. LexaMed's team of industry professionals has over two centuries of pharmaceutical and medical device experience. The skill-sets of our consultants are complementary and allow us to address situations of any subject or scope with technically compliant, practical comprehensive solutions. Our consultants are experienced in Quality Systems, Validation – product, process and equipment, Aseptic operations, Sterilization – radiation, ethylene oxide, VHP, steam, liquid, Regulatory Compliance, Microbiology, Engineering and Analytical Methods. LexaMed laboratories are ISO certified and provide quality services in microbiology and chemistry. Lab services include many offerings such as D and z-value determinations, BIER unit exposures, package integrity and container closure challenges, stability and accelerated aging under ICH specified conditions. Dedicated laboratory space and personnel are available for the execution of custom R&D protocols. LexaMed is ISO 13485 Certified, holds a State of Ohio drug license and DEA registration, retains a FDA registration for both medical devices and pharmaceuticals, and maintains active memberships in AAMI, ACS, ASM, ISPE, PDA, and RAPS.

Locus AG biologicals are the solution farmers have been waiting for. Our microbial-based products are specifically formulated for targeted, proven outcomes including improved soil quality, expanded root growth, enhanced nutrient uptake, increased plant vigor, and higher yields and grower ROI. These biologicals aren’t just “nice to haves” — they’re Simply Vital to the future success of any farming operation. Learn more by visiting LocusAG.com.

Matrix Meatsdevelops and manufactures nanofiber scaffolds to support the production of cultivated meat.3Dnanofiberscaffolds improvemeat production.

Medpace is a scientifically-driven, global, full-service clinical contract research organization (CRO) providing Phase I-IV clinical development services to the biotechnology, pharmaceutical and medical device industries. Medpace’s mission is to accelerate the global development of safe and effective medical therapeutics through its high-science and disciplined operating approach that leverages local regulatory and deep therapeutic expertise across all major areas including oncology, cardiology, metabolic disease, endocrinology, central nervous system and anti-viral and anti-infective. Headquartered in Cincinnati, Ohio, Medpace employs approximately 5,800 people across 43 countries.

Meridian is a fully integrated life science company that develops, manufactures, markets and distributes a broad range of innovative diagnostic test kits, rare reagents, specialty biologicals and components. Utilizing a variety of methods, our diagnostic tests provide accuracy, simplicity and speed in the early diagnosis and treatment of common medical conditions, such as infections and lead poisoning. Meridian's diagnostic products are used outside of the human body and require little or no special equipment. The Company's diagnostic products are designed to enhance patient well-being while reducing the total outcome costs of health care. Meridian has strong market positions in the areas of gastrointestinal and upper respiratory infections, and blood lead level testing. In addition, Meridian is a supplier of rare reagents, specialty biologicals and components used by organizations in the life science and agri-bio industries engaged in research. Many companies also utilize Meridian's products as components in the manufacture of diagnostics. The Company markets its products and technologies to hospitals, reference laboratories, research centers, diagnostics manufacturers, and agri-bio companies in more than 70 countries around the world. Meridian's website address is www.meridianbioscience.com.

A NEW Test to Determine Breast Cancer Risk....A Breakthrough!!!! Women with lumps in their breasts have to make a difficult decision whether or not to undergo treatment. For these women, a NEW TEST can help in the assessment of their cancer risk and hugely facilitate their decision-making process. We have studied a protein (called hOPN-c), which serves this purpose. The presence of hOPN-c in a lump indicates an elevated risk for breast cancer down the road, and the more of it is detected the more substantive is the risk. A pathologist can simply apply this test to a biopsy

MiCo Biomed USA is a biotechnology company that offers Optimiser™ Plus Microfluidic Plates for Life Science and Diagnostic Immunoassays.

MCRC in Dayton, Ohio is a psychiatric medication research center specializing in medical research studies for a range of mental health disorders.

NanoLogix® is a biotechnology company that specializes in rapid diagnostics of viable microorganisms and viruses through petri plates with unique vacuum FlatPack® technology for extended shelf-life.

Navidea Biopharmaceuticals, Inc. (NYSE: NAVB) is a leader in precision medicine with immuno-targeted products designed to help identify the sites and pathways of undetected disease and enable better diagnostic accuracy, clinical decision-making, targeted treatment and, ultimately, patient care. Applying our Manocept™ technology, Navidea seeks to develop next-generation targeted diagnostics and therapies for cancer, autoimmune conditions, and other inflammatory diseases, with an initial focus on personalized Rheumatoid Arthritis diagnostics. The company, founded in 1983, maintains headquarters in Dublin, Ohio.

NeoProteomics, Inc. offers covalent labeling (CL) and mass spectrometry (MS) services to industry to characterize therapeutic proteins.

Neucore’s proprietary Fibroblast-Derived Engineering Extracellular Vesicles (FiXE™) platform enables unparalleled cell-targeted delivery of genetic therapeutics to address complex diseases and advance the next generation of functional skincare. The FiXE platform harnesses the unique regenerative biology of fibroblasts—cells central to tissue repair and structural integrity—to engineer exosomes capable of restoring function at the cellular level, offering a cost effective, scalable solution for genetic medicine and dermatology.

NeuroTherapia, Inc. is a clinical-stage company developing oral, small molecule therapeutics that inhibit microglia cells, which are known to express proteins that drive inflammation. The company was founded in 2015 by the Cleveland Clinic and two of its physician scientists.

Oligonucleotides are giving rise to a new generation of therapeutics—and Nitto Avecia is helping lead the way. With more than 25 years' experience in oligonucleotide development and production, we are the partner of choice for pharmaceutical innovators creating new drugs with the power to transform treatment for a wide range of diseases. In partnership with Nitto Avecia Pharma Services, Nitto Avecia is the first CMO that offers a comprehensive, end-to-end oligonucleotide solution. This offers the advantage of a single, expert partner handling the entire process—from drug substance through drug product manufacturing—with flexible solutions and consistent reliability and quality.

Nordson MEDICAL (Nasdaq: NDSN) is a global expert in the design, development, and manufacturing of complex medical devices and component technologies. We serve interventional, surgical, and specialized markets as the engine of innovations that save or enhance patients’ lives. We work with companies at any point in the product lifecycle to bring their innovative ideas to life. As a single-source partner, we enable our customers to save costs and speed time to market. Our 3 areas of focus provide customers with a complete solution: • Design & Development • Components & Technologies • Finished Device Solutions We offer innovative tools, technologies, and solutions that can help your team bring critical technologies and complex devices to market faster and more cost effectively. • Our online store (https://bit.ly/3PapqHV) offers several configurations of components and technologies • Our innovative prototyping tools and project accelerators help you design and develop clinically effective, complex devices and technologies — in less time and at less cost • Our experienced team comprises more than 250 technical staff, including 100+ with advanced engineering degrees Company & Culture: Quality is paramount in everything we do because our components and finished devices are used to save or enhance patients’ lives every day. We have developed a culture of continuous improvement and a single global quality system to ensure reliable, consistent product performance. Our commitment to excellence is at the heart of our interactions with customers, suppliers, and coworkers. Our quality mantra is “Quality Works Here.” View our Online Store to see the large selection of components that we currently offer: https://bit.ly/3PapqHV

NovAccess Global is a biomedical company accelerating and investing in novel cancer diagnostics and therapeutics.

NovelMed Therapeutics is a privately held biotechnology company that has developed cutting-edge highly selective therapeutics for complement-mediated diseases.

Noxsano is a wound care company dedicated to developing medical dressings that deliver bio-signaling molecules to enable effective treatment of acute and chronic wounds. Noxsano's patent pending technology has been shown in pre-clinical testing to restore normal wound healing to ischemic (chronic) wounds and accelerate the healing of acute and burn wounds

Olon Ricerca Bioscience is a pharmaceutical company that specializes in Active Pharmaceutical Ingredients (API) contract development and manufacturing, as well as generics supply.

Onconetix (formerly Blue Water Biotech Inc.) (Nasdaq: BWV) is a biopharmaceutical company focused on developing transformational therapies to address significant health challenges globally. The company holds the rights to proprietary technology developed at the University of Oxford, Cincinnati Children's Hospital Medical Center (CCHMC), and St. Jude Children's Hospital. The company is developing a universal flu vaccine that will provide protection from all virulent strains in addition to licensing a novel norovirus (NoV) S&P nanoparticle versatile virus-like particle (VLP) vaccine platform from CCHMC to develop vaccines for multiple infectious diseases, including norovirus/rotavirus and malaria, among others. Additionally, Blue Water Vaccines is developing a Streptococcus pneumoniae (pneumococcus) vaccine candidate, designed to specifically prevent the highly infectious middle ear infections, known as Acute Otitis Media (AOM), in children.

Optimvia is a biopharmaceutical company specializing in engineering enzymes and their cofactors to synthesize complex therapeutic molecules. The company leverages its ADEPT™ platform to engineer biosynthetic heparin and aims to manufacture non-animal derived heparin as proof of principle for its platform.

Orange Grove Bio was established with a clear vision: to bridge the gap between promising research programs and the successful development and commercialization of transformative therapies. Our company is driven by the recognition of the disparity in venture capital investment across different regions of the United States, often resulting in groundbreaking discoveries going unexplored and potentially life-changing treatments failing to reach the patients who need them most. Based in Cincinnati, we strategically partner with prominent institutions and researchers across the Midwest, Southeast, and Mid-Atlantic regions. By fostering strong partnerships built on a shared commitment to innovation, our aim is to ensure that discoveries from these regions translate into life-changing treatments for patients, unlocking the full potential of the most promising research programs.

PaternityUSA.comprovides comprehensive DNA testing services for paternity, ancestry, and other genetic inquiries.

Solving GPCR structures

P&G was founded more than 185 years ago as a soap and candle company. Today, we’re one of the world’s largest consumer goods companies and home to iconic, trusted brands, including Always®, Charmin®, Braun®, Fairy®, Febreze®, Gillette®, Head & Shoulders®, Oral B®, Pantene®, Pampers®, Tide®, and Vicks®. The design, development, growth and success of these products—and many more—is thanks to the innovative and insightful minds of our people. From Day 1, you’ll help make everyday life easier for our 5 billion consumers. There is no single equation for success at P&G, because no two P&G people or careers are alike. Just as we strive to deliver a superior consumer experience, we aim to deliver a superior employee value equation as well. With our large global footprint, there are many opportunities to work with P&G in multiple locations. We offer opportunities in approximately 70 countries and continually aim to attract, reward and advance the finest people in the world. Here, we want you to get your career off to a fast start. That's why we don't have any rotational development programs or gradual ramping-up periods: you’ll be able—and encouraged—to dive right in from Day 1. Join us and help make life better through meaningful work that makes an impact from Day 1.

ProtoKinetix (PKTX) is a research and development company leading the way in cell survival solutions. Its patented anti-aging glycopeptide (AAGP) is a revolutionary discovery with incredible opportunity to shape the future of ophthalmology, dermatology, transplant support and biomanufacturing. Based on a molecule found in nature and harnessed by a world-class research team, this anti-aging glycopeptide helps more cells survive longer and has the capability to change health care forever. With AAGP, health therapies will become more effective, more affordable and more accessible. We will get closer to cures for conditions such as Type 1 diabetes, macular degeneration, heart disease and stroke. More lives will improve, and more people will get the treatments they deserve. ProtoKinetix has harnessed a molecule found in nature with the power to transform lives and the future of health care. Founded in 2002, ProtoKinetix secured a patent for anti-aging glycopeptide (AAGP), a naturally-occurring molecule that regenerates cells for animals surviving in arctic temperatures. AAGP has gone through a series of tests in laboratories throughout Europe and North America conducted by some of the best researchers in the world. Backed by a decade of promising clinical research, all trials to date have shown that AAGP is safe, stable and effective in protecting and regenerating cells. This molecule could be the link to improved treatments for transplants, Type 1 diabetes, macular degeneration, stroke, heart disease and so much more. There is endless potential, and we’ve only seen the tip of the iceberg. Become part of the next great medical discovery.

Q Laboratories is an ISO/IEC 17025 Accredited, cGMP/GLP compliant, FDA Registered laboratory, that provides microbiology and analytical chemistry laboratory services to companies around the world. Q Laboratories can perform analyses on food & beverages, raw materials, pet food, pharmaceuticals, cosmetics, OTCs, dietary supplements, medical devices, and health and beauty care products.

In 2021 Redi.Health was founded with a simple goal: Empower patients to take control of and contribute to their health journey. We believe that when it comes to healthcare, the patient is often forgotten and left to navigate the overwhelming world of healthcare on their own. To fix this problem we developed Redi.Health. Redi puts more simplified tools in the hands of patients than ever before and creates novel pathways of connectivity to the support and resources patients wouldn’t otherwise have access to. It’s simple – we believe in patients and giving them the tools to take control of their health.

S4 Medical is committed to developing solutions for safer and more effective catheter ablation treatment for atrial fibrillation.

Sermonix Pharmaceuticals, founded by David Portman, MD—a leading clinical researcher and expert in women’s health—focuses on developing targeted therapeutics to treat ESR1-mutated metastatic breast and gynecological cancers.

SPR Therapeutics is a medical device company focused on non-opioid, non-surgical, minimally invasive pain management solutions. The company is dedicated to improving the lives of individuals living with acute and chronic pain through innovative treatments that aim to provide meaningful relief without the need for opioids or surgery. The primary product offered by SPR is the SPRINT PNS System, a neuromodulation treatment that delivers significant and sustained relief from chronic pain. This system is a first-line peripheral nerve stimulation option that reconditions the central nervous system without requiring permanent implants or risking addiction. It is cleared for use up to 60 days and has been studied for various pain conditions, including low back pain and post-operative pain. Headquartered in Cleveland, Ohio, with additional offices in Chapel Hill, North Carolina, and Minneapolis, Minnesota, SPR has a senior management team with extensive experience in the pain management and MedTech sectors. The company has been recognized as the fastest-growing private company in Northeast Ohio, reflecting its rapid growth and influence in the medical device industry.

Standard Bariatrics® is committed to creating superior Bariatric/Metabolic Surgery clinical and economic outcome solutions for Patients and Healthcare Providers. We are leading the charge to harmonize the sleeve gastrectomy procedure with the Titan SGS® Stapling Technology, an anatomy-based approach to sleeve gastrectomy performed laparoscopically. By working alongside bariatric surgeons, we are actively developing a portfolio of medical devices to assist surgeons in shaping the future of Bariatric Surgery.

STERIS is a leading provider of infection prevention and other procedural products and services, focused primarily on healthcare, pharmaceutical and medical device Customers. MISSION WE HELP OUR CUSTOMERS CREATE A HEALTHIER AND SAFER WORLD by providing innovative healthcare and life science products and services around the globe. VISION We strive to be a GREAT COMPANY. We provide world-class products and services for our Customers, safe and rewarding work for our people, and superior returns for our Shareholders. • $5 Billion in revenue in FY24 • More than 17,000 Associates worldwide • Over 4,000 Customer-facing professionals • Listed on the New York Stock Exchange under the symbol “STE” To learn more, visit www.steris.com and careers.steris.com.

Develops software to analyse, interpret and investigate DNA profiles.

Synapse Biomedical Inc (SBI) was founded in September 2002 to commercialize the NeuRx Diaphragm Pacing System (DPS)® that has been developed over a twenty-year period at Case Western Reserve University and the University Hospitals of Cleveland. The innovative research performed at these institutions has led to significant advances in the state of the art of electrical stimulation for the treatment of chronic respiratory insufficiency. This innovation allows the technology to meet clinical needs, beyond the ability of the currently available systems, in Spinal Cord Injuries, in the diaphragm conditioning in muscular dystrophies (such as ALS) and in respiratory short-term intensive care settings.

Community Tissue Services is a quality, ethical provider of services to donor families, medical communities, recipients, and community partners through recovery, processing, and distribution of tissue grafts. Community Tissue Services strives to be on the forefront of new graft development and biotechnology to better serve recipients and medical professionals.

Trailhead Biosystems merges developmental biology and cell therapeutics with cutting edge hardware, and computerized experimental design and analysis to perform process-specific parameter optimization for customers seeking to develop cell therapies. Implementing Quality by Design (QbD) principles, cell culture optimization is done by utilizing Design of Experiment (DoE) theory combined with Multivariate Data Analysis (MVDA). This allows Trailhead to generate mathematical models of the biological system, understand the effector-response relationship in cell culture, and provide a systems biology analysis of the differentiation space. DoE-based experimental design and robotic execution greatly reduce the number of experiments and time needed for optimizing a large number of variables simultaneously. You will see that Trailhead Biosystems is novel from its ability to: Have computer-based experimental designs executed for advanced cell culture Gain knowledge into how cell culture affects gene expression in cells Mathematically model the effector/response space so virtual experiments can be performed and enable exploration of cell biology to predict how additives will create desirable cell culture fates Address optimization challenges for cell purity and potency Understand the variance in cell manufacturing methods

We are a US biotech company focused on restoring cell health and resilience, with profound initial indications for the treatment of cancers and rare diseases, the protection of multiple organ injuries, and the effective reversal of aging. We are looking for investors, development partners, or licensees. Interested parties please contact us for further information and discussions.

University Hospitals is a healthcare provider that offers medical services and patient care.

Versiti was founded with the belief that together, our blood centers can better serve people’s urgent need for life-saving healthcare. That we can strengthen and restore the health of our communities while conducting groundbreaking research. That we can integrate scientific innovation, medicine, and service in ways that no other blood health organization can match. We’re driven by the urgency of our work and inspired by the generosity of the people we rely on for life-saving donations. We have the privilege to safeguard these gifts and ensure they go where the need is greatest, in our communities and beyond––and our hospital and healthcare partners across the nation rely on the speed, safety, and availability of these gifts. Our people are driven by a relentless curiosity. As the home of the world-renowned Blood Research Institute, we attract leading blood health researchers from around the world who are passionate about advancing personalized medicine. We conduct focused research in areas like cellular therapies, oncology, and genomics, to make a difference in the lives of people through the healing potential of blood. People need people. There is no substitute for blood, organs, tissue, or bone marrow. They are precious. They are perishable. And the need for them is vital. As a partnership of blood centers, we’re far stronger together than we are alone. Ultimately, the meaning of our work is found in the lives we save and the people we serve. Our dedication to service and safety will enable us to become the partner of choice for hospitals everywhere. Our commitment to scientific rigor can save lives and advance the field of personalized medicine. And our commitment to building deep relationships with our donors will transform Versiti into a beacon of hope, care, and innovation in the communities we call home.

Viscus Biologics was founded in 2012 to help companies solve complex challenges ranging from ideation to high volume production. We are specialists in natural polymer and extracellular matrix materials, with the ability to develop and manufacture highly-specialized components, devices, and products needed to restore tissue to a healthy, functioning, and durable state. A LIFE SCIENCE PARTNER Whatever biomaterial needs you may have, companies can depend on Viscus Biologics for succesful product realization, quality manufacturing and timely distribution. With over ten years of operating excellence, we are thoroughly experienced with established procedures, policies, and a quality system to support product realization. PROVEN PROCESS The established D4 (Define, Discover, Develop, Deliver) process ensures that components, devices, and products are successfully realized and optimized for high performance. ROBUST SUPPLY CHAIN Our robust and domestic centered supply chain and partner network ensures consistency, cost-containment, availability, and timely delivery of components, devices, and products.

XaTek is a biotechnological company that focuses on developing a portable sensing system that can assess the clotting ability of a person’s blood.