List of Biotech, Pharmaceutical & Life Sciences companies in Minnesota - 108

4C Medical Technologies, Inc. is a medical device company developing a novel minimally invasive solution for the treatment of mitral regurgitation (MR). We are the first transcatheter MR therapy that directly addresses mitral regurgitation without replacing the native mitral valve, thus preserving the native mitral annulus and left ventricle. The device is positioned supra annular to the leaking native mitral valve to stop the leak from entering the left atrium. Its atrial only fixation ensures minimal disruption to critical cardiac structures within the left ventricle including the chordae tendineae and the left ventricular outflow tract. Our initial focus is to develop a novel therapy for mitral regurgitation (MR), and subsequently for tricuspid regurgitation (TR).

Access Genetics, LLC is a privately held Minnesota-based company founded in 2001 by Dr. Ronald McGlennen, an internationally recognized molecular diagnostics expert with over a decade of experience in implementing and developing molecular genetic laboratories. As a medical technology service company, we offer turnkey solutions to assist laboratories in the implementation of molecular genetic testing by recommending a tailored, cost-effective and state-of-the-art suite of hardware, software, prepackaged materials and supplies, process guides, custom tools, staff training, technical support, telemedicine interpretations, and other optional consultative services. This comprehensive service package makes Access Genetics unlike other companies in the genetic testing market that may only provide a piece of the testing puzzle. Our Mission is to improve the availability and utility of diagnostic genetic testing through a base of laboratory providers using our Web-Enabled DNA Testing Model. We partner with qualified clinical labs to enable them to build a quality in-house molecular genetics program that is simple, fast, economical and complete.

Alpheus Medical, Inc, is a privately held company based in Oakdale, Minnesota, developing a novel sonodynamic therapy platform targeting solid body cancers. The company's lead product utilizes a novel, non-invasive drug device combination for outpatient treatment of recurrent glioblastoma multiforme (rGBM). Alpheus Medical's work has been developed in conjunction with some of the most accomplished names worldwide in neuro-oncology, and with support from the American Cancer Society and National Brain Tumor Society.

Amerilab Technologies is a pharmaceutical manufacturing company that specializes in developing, manufacturing, and packaging effervescent tablets and powders in stick packs and sachets.

AngioInsight, Inc. is a digital health company based in Ann Arbor, Michigan, specializing in artificial intelligence for cardiovascular diagnostics. Founded in 2018, the company develops AI-driven solutions aimed at improving the accuracy and efficiency of diagnosing and managing coronary artery disease (CAD). The AngioAI+ platform is a key offering, designed for real-time assessment during angiography. It provides actionable insights by detecting microvascular dysfunction and quantifying stenosis severity. Additionally, AngioInsight offers fully automated angiogram analysis, which processes coronary angiogram videos to support clinicians in making informed treatment decisions. The company's technology integrates seamlessly into existing clinical workflows, enhancing resource allocation and patient outcomes. AngioInsight has received significant funding, including grants and investments, to support its innovative approach. The company is actively engaged in clinical studies to validate its platform's efficacy, particularly in addressing diagnostic gaps in cardiovascular care. Its solutions are targeted at cardiologists and healthcare institutions that perform millions of angiograms annually.

Ani-Logicsmakes nutritional supplements, minerals, and attractants that can be added toto deer feed to attract deer and promote antler growth. These deer feed supplements providevitamins, chelated minerals,essential oils, and probiotics designed to optimizethe immune system.

ANI Pharmaceuticals, Inc. (Nasdaq: ANIP) is a diversified biopharmaceutical company serving patients in need by developing, manufacturing, and marketing high quality branded and generic prescription pharmaceutical products, including for diseases with high unmet medical need. Our team is focused on delivering sustainable growth by scaling up our Rare Disease business through the successful launch of our lead asset, Purified Cortrophin® Gel, strengthening our generics business with enhanced research and development capability, innovation in established brands and leveraging our U.S. manufacturing capabilities. For more information, please visit our website www.anipharmaceuticals.com.

Aria CV, Inc: Improving the lives of patients suffering from the disease of pulmonary hypertension.

For more than 50 years, ARKRAY has been committed to producing safe, reliable, effective products; from developing the world's first HbA1c Analyzer, to the first blood glucose monitoring system for Long-Term Care. Today, ARKRAY manufactures cost-effective diabetes care products and clinical chemistry equipment that are simple, convenient and easy-to-use, and also serves as a private-label blood glucose meter manufacturer for the world's largest retailer. ARKRAY prides itself on putting customer service first, with personalized training, industry expertise and on-going support.

August Schell Brewing Company is a food & beverages company based out of 1860 Schells Rd, New Ulm, Minnesota, United States. We make beer that is steeped with history, malted with integrity, hopped with innovation, fermented with perseverance, aged with experience, poured with expertise, laced with character, and consumed with celebrating all of life's victories.

Aurora Pharmaceutical - We are creating the products you want by using innovative, state-of-the-art, environmentally friendly technologies. … Devoted to the development of innovative products •Improved formulations utilizing state-of-the-art ingredient technologies •Committed to taking advantage of sustainable green technologies •Enhanced product performance •Engineered for competitive advantage in the marketplace •Science-based marketing support for our trading partners

BioMatrix International was established to vertically integrate product development for animal feed and horticultural additives. We create innovative products with an emphasis on developing novel and patentable technologies. Our products are customized to meet individual needs while minimizing environmental impact. We specialize in agricultural, companion animal, and aquacultural feed additives, as well as horticultural amendments.

Birchwood is a healthcare company that offers incontinence and wound care products to healthcare professionals and patients.

BlueAllele is working to address the unmet therapeutic challenges in gene editing. Our approach is based on the core principles of innovating and developing the next level of safe and effective treatments for patients with genetic disorders. Our team excels at correcting genes at the DNA level, and has core strengths to move the field forward and develop new therapies.

Cambridge Technologies is an independent owner-operated custom vaccine company working with veterinarians and livestock producers to provide solutions to animal health problems. We use cutting-edge molecular diagnostic and manufacturing techniques to manage the entire custom vaccine process and to provide you with the best possible solutions for managing emerging health problems. Diagnostic and research scientists work in a modern laboratory specializing in personalized service. Techniques including metagenomics, genetic sequencing, qPCR, culture, sensitivity and serology will be employed as needed to precisely determine the right isolates needed for vaccine production. Research scientists alongside the diagnosticians keep Cambridge on the cutting-edge of isolate identification and characterization. Cambridge Technologies vaccines are formulated and produced at our USDA-licensed 37,000-square-foot manufacturing facility featuring a state-of-the-art fermentation suite. The vaccine production team has extensive experience in diagnostics, R&D, quality control, regulatory affairs, and both commercial and custom vaccine production. Vaccines from Cambridge Technologies are truly customized to the customer’s needs, including a range of adjuvant choices, label options, and SoliDose implant delivery in bovine products.

Cardiovascular Systems, Inc. (CSI) is committed to providing innovative solutions for the revascularization of patients with complex coronary and peripheral artery disease (PAD). Our primary focus is helping physicians conquer even the most difficult disease states, including the challenge of arterial calcium for the millions who suffer from PAD and Complex PCI. CSI is committed to clinical rigor, constant innovation, and a defining drive to set the standard in safe, effective, economical medical devices that improve patient outcomes. We are equally committed to creating an invigorating work environment for people who align with our Core Values of accountability, integrity, excellence, courage, velocity, and community. When each of our employees lives our Core Values, we're doing everything we can to achieve our mission: Saving Limbs. Saving Lives. Every Day. It is the policy of CSI to provide equal employment opportunity (EEO) to all persons regardless of age, color, national origin, citizenship status, physical or mental disability, race, religion, creed, gender, sex, sexual orientation, gender identity and/or expression, genetic information, marital status, status with regard to public assistance, veteran status, or any other characteristic protected by federal, state or local law. In addition, CSI will provide reasonable accommodations for qualified individuals with disabilities. For more information, visit www.CSI360.com or connect with us on Twitter and Facebook. Read important safety information (https://csi360.com/indications-statements-important-safety-and-risk-information/).

Celcuity is a clinical stage biotechnology company that discovers previously undetectable cancer drivers and develops drugs to treat them.

For the last ten years, ChRi Labs has built powerful relationships with some of the largest companies in the world to further progress their dynamic positions in the analytical testing marketplace. ChRi Laboratories is an FDA contract laboratory that partners with companies to perform various analytical techniques for drug formulations and products. From R&D through Commercialization, our testing can help identify a products' identity, strength, quality, purity, and potency. Our ISO 17025 Accreditation and a robust internal quality system, displays the true integrity of the work we do. With companies today hyper-focused on improving quality and safety, we ensure that your products exceed quality, stability, and safety standards.

CoraVie Medical's implantable, continuous blood pressure monitor informs treatment decisions to improve lives. The end to end solution improves patient compliance to monitoring and improves blood pressure reliability and actionability. By monitoring trends over day and night, CoraVie enables timely notification of changing health status.

Courante Oncology is a full-service clinical research provider specializing in oncology product development. We offer a wide range of clinical trial management and support services to the pharmaceutical and medical device industries, including project management, clinical site monitoring, quality assurance, and medical writing servies. We believe the challenges of oncology clinical trials require a research team that is uniquely experienced and trained. Our strength lies in our collective experience and our ability to adapt to and meet our clients' specific research needs.

Cryosa is a clinical stage company developing a treatment for moderate to severe Obstructive Sleep Apnea (OSA). We believe that mask-free, hose-free, implant-free treatment is possible. Everyone is free to sleep, free to rest and free to live brighter days.

CVRx is a commercial stage, public (NASDAQ: CVRX) medical devices company located in Minneapolis, Minnesota. The company has developed proprietary implantable technology for the treatment of high blood pressure and heart failure. Barostim™ triggers carotid baroreceptors - the body's own natural blood flow regulation system - which signals the brain to regulate cardiovascular function. Patient Stories on CVRx: The accounts and quotes of patients are genuine and documented. These stories represent a unique individual experience and does not provide any indication, guide, warranty or guarantee as to the response other people may have to CVRx technologies. Barostim is a prescriptive device. For a list of all potential benefits and risks go to www.cvrx.com/benefit-risk-analysis/

Cytotheryx is a platform technology company focused on the development of a high-quality, consistent source of primary human hepatocytes (PHH), the functional cells of the liver. Based in Rochester, Minnesota, Cytotheryx is using innovative technology to increase the supply of available cells for use by pharmaceutical companies, biotechnology companies, and academic research institutions. Primary human hepatocytes are used widely in research, making them vital to continued scientific and therapeutic breakthroughs. However, a limited supply of liver cells prevents ongoing growth. Cytotheryx is opening doors for how we treat liver disease, develop therapeutics, advance research, and beyond.

DiaMedica Therapeutics is a clinical-stage biopharmaceutical company that is developing innovative treatments where there is significant unmet clinical need or where no current therapies are available with the focus on neurological and kidney diseases.

Donaldson Company helps solve some of the world's most complex filtration and contamination control challenges. As a global leader in the filtration industry, we pride ourselves on our innovative technologies and solutions, backed by a talented and dedicated team of employees. Our filtration technologies and products are used every day in a variety of industries and environments, including aerospace, agriculture, construction, food and beverage, manufacturing, mining, power generation, transportation and many more. Our success comes from our 14,000+ employees, the support our customers receive, and more than 140 manufacturing and distribution centers on six continents.

Endogenex, in partnership with Mayo Clinic, aims to revolutionize treatment options for individuals with type 2 diabetes (T2D). Endogenex's innovations focus on resetting the body's metabolic signaling system by harnessing its natural regenerative capabilities to improve metabolic function. Through the development of the ReCET System and the novel application of precise, controlled, non-thermal pulsed electric fields, Endogenex is establishing a new era in treatment options for people living with T2D, helping patients regain control of their blood glucose levels and slow disease progression. Endogenex is a privately held, clinical-stage company based in Minneapolis, MN.

Envoy Medical (Nasdaq: COCH) is a hearing health company focused on providing innovative technologies across the hearing loss spectrum. Envoy Medical has pioneered one-of-a-kind, fully implanted devices for hearing loss, including its fully implanted Esteem® active middle ear implant, commercially available in the U.S. since 2010, and the fully implanted Acclaim® cochlear implant, an investigational device. Envoy Medical is dedicated to pushing hearing technology beyond the status quo to improve access, usability, compliance, and ultimately quality of life.

Tissx sources, manufactures and supplies tissue products and services for cardiac, vascular and other specialty surgeries. Our goal is to make affordable high quality tissue products available worldwide. We develop and manufacture products including fixed pericardial tissue patches and valve repair products. Tissx also works with corporations to source and supply tissue, provide OEM services and develop tissue bioprosthetics.

Evia Bio™ is a life science innovation company enabling the growing cell therapy market. We provide new non-DMSO cryopreservation solutions developed by world-leading cryobiologist, Allison Hubel, PhD. We partner with cell therapy companies looking to advance their products to clinical trials and commercialization. Our solutions unlock the full potential of emerging life-saving therapies through the use of all-natural organic compounds to protect the integrity of cells during cryopreservation and patient safety at the point of care. Please visit www.eviabio.com.

FastWave Medical is developing novel, cost-effective intravascular lithotripsy systems for calcific artery disease. Learn more here.

Overactive bladder (OAB) affects over 15 million women in the US. The sudden, urgent desire to pass urine greatly limits quality of life. Current treatments are not optimal, requiring frequent, time-consuming office visits, awkward vaginal probes, medications with potential side effects or surgery. Those suffering with OAB often consider the therapies too cumbersome and forgo treatment, opting instead to place limits on their life to accommodate the symptoms. Neuromodulation for OAB involving electrical stimulation of the sacral nerve is a proven and established therapy. However, despite being commercially available for over a decade only a small fraction of indicated patients have been treated. The cost and invasiveness of the surgery are often cited as concerns by prospective recipients. FemPulse has developed a novel, wearable medical device designed to deliver neuromodulation therapy directly to the nerves that regulate bladder function, without the need for surgical implant. The small device is easily placed by the patient herself and controlled with a smartphone app. The company is currently conducting clinical evaluations in the United States.

For ordering information, please contact: 3M+KCI at +1-800-275-4524, KCI Express® https://mykci.com/kci-express, or Your local 3M+KCI Sales representative ________________________ Managing ostomy complications and intestinal fistulas is a challenge. A high output ostomy stoma or enteric fistula can produce two to seven liters of effluent per day which can cause edema, wound formation, complications and infections. To improve the management of patients with enteric fistulas and high output ostomy stomas we developed the Wound Crown®, Fistula Funnel® and Isolator Strip®. These barrier devices have been used effectively to compress the surface of the body around enterocutaneous fistulas, enteroatmospheric fistulas, ostomy stomas, and wound drains with moderate to high output levels to seal and protect the perimeter skin from effluent and reduce edema.

Francis Medical is developing minimally invasive treatment solutions for prostate, kidney, and bladder cancer through the use of convective thermal water vapor. Currently, the company is in clinical trials for ablating cancerous prostate tissue. Founded in 2018, Francis Medical is located in Maple Grove, Minnesota. Francis Medical, Inc., formerly named NxPhase Medical, Inc., is a company that was created after Boston Scientific (BSC) acquired NxThera, Inc. in April of 2018. As a part of the BSC/NxThera transaction, a separate and independent entity, NxPHASE Medical, Inc. (“NxPHASE”), was established, and shares of NxPHASE were distributed to the shareholders of BSC/NxThera. In addition, BSC/NxThera granted NxPHASE a license to utilize BSC/NxThera’s convective vapor ablation technology to develop, evaluate, and commercialize certain devices to treat prostate, kidney and bladder cancer (“NxPHASE Field of Use”), while BSC/NxThera remains focused on the treatment of benign prostatic hyperplasia. Late in 2018, NxPhase Medical, Inc. went through a rebranding process and selected Francis Medical, Inc. as its new brand and identity. The name and foundation of the company are a tribute to and legacy of Michael Hoey’s (founder/inventor) father, Francis Hoey, whose life was ended by prostate cancer with treatments that had harsh implications on his normal daily living.

Our mission is to enable a world where everyone's health is informed by genetics. As a leading telegenetics care delivery company, we make genetics care accessible and actionable for patients throughout the U.S. and Canada through seven-day a week access to genetic services. We partner with health systems, genetic testing laboratories and biopharmaceutical companies. We accelerate, grow and provide service to their patients by launching genetics programs from the ground up, improving the scale and efficiency of existing genomic medicine programs, and providing genetic expertise and services to support clinical trials and sponsored genetic testing programs. With the largest national network of telehealth genetic counselors – averaging 10 years clinical experience – We have delivered more than 200,000 genetic counseling encounters, scaling to more than 8,500 patients per month and helping health systems expand network reach to more patients by delivering genetic care to patients anywhere, seven days a week. We are a covered benefit for 130 million people in the U.S. Through our nationwide virtual care delivery model, we provide genetics care to patients when and where it is most convenient, reducing patient wait times from as much as 18 months to one week. We have an extensive team of clinicians, including medical geneticists, genetic counselors, physicians and pharmacists. Our clinical specialties include oncology, reproductive health, cardiology, pediatrics, rare disease and proactive health.

The company offers products and services in:advanced probiotics and feed additivesgenetically engineered probioticsassays and screens of probiotics, andcustom probiotic fermentation.

Geneticure optimizes prescription drug therapy by using patients’ DNA to guide their blood pressure treatment with a new, actionable tool, supported by clinical evidence to help you provide even better care for your hypertension patients.

GRIP Molecular is developing a novel, patent-protected, chip-based electronic biosensor that will provide lab-grade diagnostic results in minutes using a mobile device at the point of need. Unlike existing diagnostic technologies, it has the capability to simultaneously detect various diseases and characterize their state of infection (infectious to immune) with a single test. GRIP uses a combination of novel nanomaterials and patented 3D printing to deliver accurate results in minutes without the burden of complex chemistry. The appearance of COVID-19 as a global health threat has increased the urgency to transform diagnostics, which the GRIP team was well into even before this threat emerged. The ability to quickly, easily and cost-effectively test for active infection and immunity at the point of need has become the new baseline for what we should expect for early detection of all kinds of disease, but particularly when fighting a pandemic level enemy. GRIP is committed to confirm the science and commercialize a new approach with a number of specific panels/products that address our most challenging diseases and chronic conditions.

Numotizine is a healthcare company that specializes in producing a patented poultice for external medical use.

Humanetics is a privately held, clinical stage pharmaceutical company located in the Minneapolis metropolitan area. Our lead candidate, BIO 300 is being developed for multiple clinical uses with a primary focus on improving treatment of solid tumor cancers. BIO 300 is being developed as an agent to both sensitize tumor cells to enhance radiation treatment efficacy and to protect normal tissues from harm. Thus, reducing common treatment related side effects such as radiation induced pneumonitis, erectile dysfunction, mucositis and xerostomia. BIO 300 is also under development for inflammatory lung diseases with an immediate focus on mitigation of pulmonary injury due to COVID-19. A recent contract from NIAID will fund a phase 2 study on BIO 300 in recovering COVID patients in an effort to stem progressive long-term lung complications, such as fibrosis. BIO 300 was licensed from the US Department of Defense, where it was originally developed to prevent injuries associated with ionizing radiation. This program is still underway with a focus on prevention of acute radiation syndrome as well as lung injury. For more information about Humanetics, please visit our corporate website at www.humaneticscorp.com.

Since 1997 IBL-America has been a supplier of in-vitro diagnostic kits, antibodies and proteins for the medical device industry as well as the medical research industry. IBL-America is active in the following areas: autoimmune, brain research, endocrinology, infectious disease, neuroscience, oncology and tumor markers. IBL-America has its own technical support staff and works in conjunction with its sister company, KMI Diagnostics, to provide expert technical service and customer support. KMI Diagnostics, Inc.(www.kmidiagnostics.com) is a CLIA certified endocrinology and research laboratory specializing in hormone and neurotransmitter testing as well as correlation studies and pre-clinical trials.

IGF Oncology, LLC Our Mission: IGF Oncology is developing novel cancer drugs that have better efficacy and lower side effects than existing cancer chemotherapy drugs.

Imanis Life Sciences has an unwavering commitment to the advancement of science. For many companies, profitability rules decision making. But at Imanis, leading scientific breakthroughs is the primary focus. We are about making a difference in the world by putting people in a better position than they were yesterday. We strive to do this by being a leader in laboratory assays and research services to accelerate the development of a broad range of next-generation therapies.

Immune IQ has developed, in collaboration with Honeywell, the Immune Reveal platform. It reads disease information from a patient's immune system in 5 minutes to rapidly identify critical diseases, many not detectable today. Our powerful diagnostic approach has a much lower cost-per-test, a greater range of disease identification, and a shorter time to results than other cellular- and mRNA-based approaches. Immune IQ's initial focus is sepsis, one of the world's greatest healthcare challenges.

InSitu Biologics is an emerging biotech company focused on development of a multi-phase prolonged release drug delivery platform for localized treatment of pain, cancer, and infection. We use disruptive technology to address unmet needs in the pain management and drug delivery markets.

We are a global food company with 150+ locations in rural America and around the world. We are 70,000+ team members strong with a dedication to responsibly meeting today's tastes while ensuring a more sustainable tomorrow.

Kindeva is a global powerhouse CDMO dedicated to manufacturing more tomorrows. Leveraging more than 100 years of innovation, Kindeva provides unrivaled expertise at every stage of pulmonary, nasal, injectable, intradermal, and transdermal therapy development and manufacturing. Whether providing holistic analytical support or scaling sterile injectable fill-finish operations, every solution is backed by extensive technological capabilities, deep regulatory knowledge, and state-of-the-art facilities across the U.S. and U.K. Kindeva’s proactive, informed solutions minimize risk and maximize confidence from ideation through commercialization, bringing high-quality products to patients in need, faster. For more information about our leading drug-device CDMO, please visit www.kindevadd.com.

LEAH Laboratories is a biotechnology company that specializes in building living therapies for pets and their people.

Liberty Oxygen and Medical Equipment enables you to stay safe and independent in your home by offering a comprehensive array of home medical equipment & oxygen [including CPAP supplies, compression stockings, bath aids, canes, wheelchairs, walkers & more] in addition to prompt, personalized care. With 7 locations in the Twin Cities metro, there's always a store convenient for you. Burnsville 14001A Grand Ave S 952-898-5008 Coon Rapids 11650 Round Lake Blvd 763-231-2177 Maple Grove 16322 County Road 30 763-494-4966 Maplewood 1715-D Beam Avenue 651-789-7500 Saint Louis Park 4820 Park Glen Road 952-920-0460 Shakopee 1667 16th Ave E, Suite 102 952-445-5454 Woodbury 1815 Radio Drive 651-789-0050

Lifecore Biomedical is a full-service contract development and manufacturing organization (CDMO) that partners with pharmaceutical and biotech companies to develop and deliver vital and complex injectable therapies. We're also a manufacturer of premium sodium hyaluronate. From formulation to commercialization, we have everything it takes to move your project to the next level, making progress possible for our partners, people and most importantly, patients. Working from state-of-the-art facilities, our people are subject matter experts, our capabilities customized, our processes and systems qualified and our infrastructure optimized to meet your most sophisticated requirements regardless of scale. Our expertise is in drug products that are challenging and difficult to formulate, sterile filter, and aseptically fill. We've been the global leader in pharmaceutical-grade sodium hyaluronate (NaHy) for nearly 40 years. Leveraging this experience alongside deep expertise and capabilities in highly viscous solutions, we create tailored solutions that solve your drug development challenges across the entire development and manufacturing lifecycle. Our capabilities: Sterile Injectable Development - Formulation Development - Sterilization Development - Process Development - Analytical Services & Stability - Engineering Services - Validation Services Sterile Injectable Manufacturing - Sterilization - Aseptic Filling - Packaging - Analytical Services & Stability

Luminary is a clinical stage CAR-T therapy company with a novel allogeneic manufacturing platform where our CAR and or TCR development utilizes gamma delta cells. What makes our allogeneic therapeutics unique are that our final drug product includes the combinatory power of both the Vẟ1 and Vẟ2 gamma delta cells giving our therapies the power of both innate and adaptive cancer clearing power. We have multiple solid tumor targets under development with a proprietary signaling method to ensure T-Cell persistence. Additionally, our Ligand BAFF CAR for hematologic cancers is designed with 3 antigen receptors specifically designed to overcome antigen escape.

Mankato Brewery is a brewery that specializes in craft beer production, reviving the brewing tradition in Mankato since 2012.

Mednet is a leading healthcare technology company specializing in eClinical solutions designed for the global life sciences community. Pharmaceutical, medical device, biotechnology, academic institutions, and Contract Research Organizations (CROs) around the world have trusted Mednet for over 23 years to deliver the technology innovation, experience and reliability they need for success. Mednet's comprehensive, EDC-centric eClinical platform, iMednet, optimizes clinical studies of all types and sizes – accelerating research with exceptional flexibility, ease-of-use, robust functionality, affordability, and stellar support. iMednet is feature-rich and uniquely designed to help sponsors and CROs get studies up and running quickly and to see them through with a full suite of native capabilities, including: randomization, trial supply management, adjudication, ePRO, payments, DICOM Imaging, and eConsent. All backed by a highly tenured and experienced support team, ensuring quality, compliance and easy onboarding of the entire research team and clinical trials sites. For more information, visit mednetsolutions.com. Mednet Solutions, Inc.

Medtronic plc is an Irish medical device company. The company's operational and executive headquarters are in Minneapolis, Minnesota, and its legal headquarters are in Dublin, Ireland. Medtronic operates in more than 140 countries and employs over 90,000 people worldwide. The company is the world's largest standalone medical technology development company.

Melodi Health offers novel technologies that improve patient outcomes for women undergoing breast surgery. Melodi Health manufactures the Melodi Matrix, designed to support the soft tissue space around a prosthetic device while delivering antibiotics to the surrounding tissue. The Melodi Matrix is currently an investigational device being studied in a prospective, multi-center, randomized, controlled clinical trial in breast reconstruction.

Mérieux NutriSciences Italia, appartenente all'Institut Mérieux, è impegnata a livello globale nella salvaguardia della salute dei consumatori e della sostenibilità, offrendo un'ampia gamma di test laboratoriali e servizi consulenziali nei settori alimentare, farmaceutico, packaging, cosmetico, ambientale. Leader di riferimento nel mercato italiano grazie ad una consolidata esperienza nei servizi analitici di chimica, microbiologia e biologia, Mérieux NutriSciences Italia adotta un approccio a 360° per fornire soluzioni pratiche e innovative ai suoi clienti mediante le attività di analisi, consulenza, audit, training, etichettatura e supporto normativo, ricerca, studi sensoriali e molto altro ancora. Giovane e dinamica, nonostante gli oltre 40 anni di storia, Mérieux NutriSciences Italia opera nel rispetto di elevati standard etici e di qualità e accoglie con favore l'opportunità di coinvolgere giovani talenti, che contribuiscono in modo significativo all'innovazione e alla crescita sostenibile dell'azienda. Visita la nostra pagina > www.merieuxnutrisciences.com/it/lavora-con-noi

Headquartered in Minneapolis, Minnesota, Metavention, Inc. is a privately held medical device company developing novel treatments for metabolic diseases

Since 1996, Minnetronix Medical has accelerated medical device breakthroughs as a design, development and manufacturing partner to leading device companies around the world. Today, through life-cycle efficiency, opportunity realization, and increased utility, the organization is creating value in key technology segments, including RF energy, fluid and gas management, optical systems, and stimulation and active wearables. From design and manufacturing services to whole product solutions, Minnetronix brings expansive industry insight and intentional technical acumen, delivering better medical devices to market, faster. Minnetronix is based in St. Paul, Minnesota. ​

What we know: - Currently, 106,000 people in the U.S. are on the waitlist for a life-saving organ transplant. - 60% of patients on the waitlist will not receive the organ they need. - 17 people in the U.S. die each day due to the lack of available organs. What we're doing: Miromatrix Medical was founded with the mission to eliminate the transplant waitlist. Headquartered in Eden Prairie, Minnesota, we bioengineer organs through our patented perfusion decellularization and recellularization technology. We take what nature designed -- a fully functioning liver or kidney -- and with our patented technology, remove all of the cells from discarded pig organs. What's left is a ‘scaffold'; all of the organ's natural design and architecture remains. Then, from the inside out, we seed new, living human cells back into the organ -- ultimately creating completely functional, transplantable organs with the potential to save thousands of lives every year.

Monteris is a private equity backed neurosurgical company focused solely on diseases of the brain. The company was founded in Winnipeg, Canada in 1999 to create neurosurgical technology that, when used by neurosurgeons, would allow them to ablate brain tumors and lesions that may be difficult to approach via traditional methods. The NeuroBlate® System is a minimally invasive robotically controlled laser thermal therapy that uses MRI-guided laser light to ablate (destroy) unwanted tissue in the brain where a lesion, or abnormal tissue, originates. Monteris has offices in Minnetonka, Minnesota, USA and Winnipeg, Manitoba, Canada.

Morari's objective is to restore confidence in male sexual health by eliminating the embarrassment and frustration of premature ejaculation (PE). PE is the most prevalent male sexual dysfunction, estimated to affect 30% of men worldwide. With a higher incidence than erectile dysfunction or an enlarged prostate, men rarely talk about it or seek treatment. The Morari product concept would allow the male who desires a delay in ejaculation to use an external device that when activated by either partner, would use neuromodulation techniques to interfere with nerve signals to delay an ejaculation. When deactivated, the elements would not interfere with nerve signals.

Applied NanoBiology™ is the intersection between nanotechnology and biology. Artoss scientists apply their knowledge of physics and biology to create new nanostructured biomaterials for bone repair. This represents A New Dimension in Bone Repair™. Artoss, Inc. currently distributes NanoBone® advanced bone graft products in the United States. NanoBone Granules and NanoBone SBX Putty have been used successfully in 400,000 cases over the past ten years in Europe and US. NanoBone performs as well as the competing gold standards for bone grafting, with lower complications than autograft. Our German partner, Artoss GmbH, has multiple issued and pending patents to protect the technology. Artoss intends to develop and introduce multiple proprietary forms of NanoBone to address specific clinical needs. This includes the use of NanoBone as an implant coating to improve osteointegration of joint replacements and spinal fusion implants.

NeoChord is a privately held medical technology company leading the advancement of beating heart mitral valve repair in patients suffering from mitral valve regurgitation. The company's flagship product, the NeoChord Artificial Chordae Delivery System, received CE market clearance in December 2012.

NeuroOne Medical Technologies is a medical device company that specializes in developing high-definition, minimally invasive thin film electrodes for the diagnosis and treatment of various neurological conditions.

Nonin Medical invented finger pulse oximetry and is a global leader in developing highly accurate noninvasive medical monitoring solutions that improve the quality of people's lives. Technology driven, we provide pulse and cerebral oximeters, capnographs, sensors, OEM/eHealth, and veterinary solutions that meet customers'​ needs today and tomorrow. Nonin Medical is headquartered in Plymouth, Minnesota, USA, and has an additional customer service center in Amsterdam, the Netherlands. We sell our products to clinicians and consumers in more than 125 countries and have more than 200 OEM partners worldwide. BUY AMERICAN QUALITY. For more information, call (800) 356-8874 (toll free US and Canada) or +1 763.553.9968. Email: info@nonin.com or infointl@nonin.com. Or visit nonin.com. Vision To improve the quality of people’s lives throughout the world by expanding the capabilities of noninvasive measurements. Mission To provide a diverse portfolio of simple, noninvasive measurements that lowers the cost of care and empowers individuals and caregivers to make better decisions. These solutions will be high quality, high performance, and easy to use. Values ■ Quality – We thrill our customers by providing the finest experience. We anticipate their needs. ■ Agility – We are fast, agile and focused. We creatively drive change. ■ People – We care about our people, foster learning and provide opportunities for growth. ■ Community – We care about supporting our communities and the lives of others. ■ Integrity – We are honest, ethical and dedicated to doing the right thing.

Nortech Systems is a leading provider of design and manufacturing solutions for complex electromedical devices, electromechanical systems, assemblies, and components. Nortech Systems primarily serves the medical, aerospace & defense, and industrial markets. Its design services span concept development to commercial design, and include medical device, software, electrical, mechanical, and biomedical engineering. Its manufacturing and supply chain capabilities are vertically integrated around wire/cable/interconnect assemblies, printed circuit board assemblies, as well as system-level assembly, integration, and final test. Headquartered in Maple Grove, Minn., Nortech currently has seven manufacturing locations and design centers across the U.S., Latin America, and Asia. Nortech Systems is traded on the NASDAQ Stock Market under the symbol NSYS. Nortech’s website is www.nortechsys.com.

Nucleus RadioPharma is a full-service Contract Development and Manufacturing Organization (CDMO) dedicated to building robust and reliable clinical and commercial supply chains for targeted radiotherapies.

Nuvaira was established in 2008 to address unmet clinical needs in the treatment of overactive airway nerves, a common disease feature of both COPD. The company offers innovative COPD therapies to help preserve patient lung health with a catheter-based system used to treat overactive airways.

We are Nuwellis, (Nasdaq: NUWE) formerly CHF Solutions. Our solutions go beyond chronic heart failure, so we've rebranded to reflect our therapeutic focus areas: heart failure, critical care, and pediatric fluid imbalance. We are a medical device company dedicated to transforming the lives of patients suffering from fluid overload through science, collaboration, and innovation. Our Aquadex SmartFlow® System gently removes fluid from adult and pediatric patients weighing 20 kg or more. Nuwellis consists of a purpose-driven team that puts patients and their providers at the center of everything we do. This is the new well. And for those whose lives and life's work are transformed by our fluid management technologies, the new well is everything. Nuwellis is headquartered in Eden Prairie, Minn., with a wholly-owned subsidiary in Ireland. The Company has been listed on the Nasdaq Capital Market since February 2012, previously branded as CHF Solutions (Nasdaq: CHFS).

Objective Biotechnology's mission is to develop high-impact technologies that enable comprehensive measurement and manipulation of biological systems at multiple scales, unlocking new research capabilities.

OneOme, co-founded by Mayo Clinic, is working to help providers incorporate pharmacogenomics into patient care by offering the RightMed Test and associated tools. The RightMed Test may help providers optimize medication selection for their patients by analyzing and reporting on 27 genes. OneOme is privately held, based in Minneapolis, MN. For more information, visit www.oneome.com and follow us here for updates.

Pace® Science and Technology Company makes the world a safer, healthier place. We partner with clients to provide the service, science, and laboratory data needed to make critical decisions that benefit us all. Through a nationwide laboratory network, Pace® advances the science of businesses, industries, consulting firms, government agencies, and others. ANALYTICAL SERVICES Pace® Analytical Services is a division of Pace® Science and Technology, providing local testing and analytical services backed by a large, national laboratory and service center network. Through in-lab, mobile, and emergency onsite containment and regulatory services, we ensure our air, water, soil, and more are safe for our communities and lives. LIFE SCIENCES Pace® Life Sciences is a division of Pace® Science and Technology committed to advancing the science of the pharmaceutical and biopharmaceutical industry by providing full-service CDMO/CRO capabilities and professional services for in-house labs through a nationwide network of service centers, manufacturing sites, and FDA-registered laboratories. COMMITMENT We believe the work our customers do is important to improving our communities and lives and are committed to supporting them through strong partnerships, delivering upon expectations, and providing exceptional customer service.

Panbela Therapeutics, Inc. is a clinical-stage biopharmaceutical company developing disruptive therapeutics for urgent unmet medical needs. The company's current focus is on the treatment of urgent unmet medical needs.

Peytant Solutions, Inc. (PSI) is a medical device company, incorporating Regenerative Human Biomaterial   with  absorbable and alloy implant technologies. Our percutaneous, biologic AmnioStent...

Phenomix Sciences is a precision medicine obesity biotechnology company on a mission to conquer obesity globally through the use of proprietary testing and personalized lifestyle guidance. The company offers the MyPhenome™ test, exclusively licensed from Mayo Clinic, which measures DNA and metabolites related to obesity to improve weight-loss effectiveness. Phenomix Sciences is committed to advancing the understanding of obesity treatment through precision medicine and believes in the power of knowledge and accurate diagnosis.

The number of patients requiring hemodialysis is expected to reach 774,000 with an annual incidence of more than 160,000 new patients per year who require vascular access for hemodialysis. Vascular access for hemodialysis is creating a special pathway in the body to cleanse the blood when the kidneys aren't working (End Stage Renal Disease). Two methods of permanent vascular access: Arteriovenous Fistula (AVF) Arteriovenous Grafts (AVG) Phraxis, Inc is a Minneapolis MN based company that has developed the EndoForce™ Venous Anastomotic Connector to provide a procedural technique for AVG implantation that may lessen the neointimal hyperplasia-induced stenosis that is associated with conventional sutured venous anastomosis. See our complete clinical study of the EndoForce™ Venous Endovascular Anastomotic Connector here: https://pubmed.ncbi.nlm.nih.gov/36895157/ And join the movement at www.phraxis.com as we seek FDA approval. The EndoForce™ Venous Anastomotic Connector is an investigational device. Limited by Federal (United States) law to investigational use.

Ponte Biosciences, Inc. is a preclinical biotherapeutic company focused on developing a cell-based bioartificial liver system to treat acute forms of liver failure. The Company's Spheroid Reservoir Bioartificial Liver (SRBAL) system was developed at the Mayo Clinic and utilizes metabolically active primary hepatocytes (liver cells) to replace and/or supplement liver function for patients with liver failure being treated in the Intensive Care Unit (ICU).

Our mission at Predictive Oncology is to change the landscape of oncology drug discovery and enable the development of more effective therapies in the treatment of cancer. By harnessing the power of machine learning, scientific rigor and biologics, we can improve the probability of success and advance drug compounds with a higher degree of confidence. We invite you to follow us to stay up-to-date about our latest developments.

Since 1989 ProMed has been recognized as a leading Contract Manufacturer of complex, intricately designed molded silicone and plastic components and assemblies for highly regulated industries. ProMed's expertise lies in applications for short-term and long-term implantable devices, drug-releasing combination devices, and specialized manufacturing for aerospace, defense, and automotive applications. We collaboratively work with our customers from prototype through production, providing over 30 years of experience related to design for manufacturability, material selection, tooling/fixturing, process development, manufacturing, and other value-added services that result in cost-effective solutions with superior quality. With four facilities spanning more than 134,000 sq/ft of office, laboratory, and Class 7 Manufacturing space, ProMed's in-house services include tooling design and manufacturing, quick turn prototyping, injection and transfer molding of components, micro molding of tightly tolerance components, insert over molding, advanced material blending of specialty additives, automated assembly, testing support for drug delivery and combination devices, as well as customized packaging services.

Recombinetics is a global leader in proprietary gene repair and gene-editing technology. Our breakthrough scientific research and development of TALEN and CRISPR (Cas9) gene editing technologies has resulted in breakthroughs in the regenerative medicine, disease research and animal agriculture. Led by a team of expert geneticists, genome engineers, and reproductive physiologists, the company is headquartered in St. Paul, Minnesota.

RespirTech, a Philips company, works with healthcare teams, patients and caregivers to provide effective airway clearance therapy with the Philips InCourage system and Philips Respironics CoughAssist T70. Our dedicated customer care team contributes to improved management of chronic respiratory conditions like cystic fibrosis, COPD, bronchiectasis and certain neuromuscular and neuromotor diseases. RespirTech's innovative products and exceptional service supports patients on their journey to better breathing. Respiratory Technologies, Inc., dba RespirTech, was founded in 2004 and acquired by Philips in 2017.

Rion is a clinical-stage regenerative medicine company focused on developing innovative exosome therapeutics that are clinically impactful, accessible, and practical for any patient, anywhere. Rion has developed Purified Exosome Product (PEP), an innovative biologic platform that optimizes the therapeutic power of exosomes for regenerative medicine.

RxFunction®, Inc. is a medical device company with a mission to design and market medical technologies that improve balance, increase mobility, and enhance confidence for patients. Walkasins® Lower Limb Sensory Prosthesis is clinically proven to improve gait and balance, and reduce the risk of falls. Walkasins replaces part of the lost nerve function for the feet. It is intended for individuals who experience numbness in their feet and struggle with mobility problems due to peripheral neuropathy. Walkasins is only available by prescription. To learn more, please visit us at www.rxfunction.com. RxFunction created Walkasins by building upon patented technology developed by co-founder and scientist Lars Oddsson, PhD. Development of Walkasins was supported by Small Business Innovation Research grants from the National Institutes of Health and is manufactured in Minnesota. RxFunction is the exclusive provider and manufacturer of Walkasins. Caution: Individual results and activity levels while using Walkasins may vary depending on many factors. There are risks associated with the use of this product and there are certain individuals who should not use the product. Only a qualified clinician can tell you if this product is appropriate for you and your individual circumstances. Please consult with your healthcare team for complete information regarding benefits, risks, and possible outcomes.

At Sanos Nutrition, we strive to help achieve "A Great Balancing Act." With global population expanding in number and affluence a dilemma is developing that requires increasing agricultural production while retaining rural economic value and reducing environmental impact. Our yeast are economically and environmentally sustainable being grown for rural livestock feed producers from locally sourced ag processing inputs without consuming more land, water and fertilizer. We produce yeast-derived nutrients to compliment and maximize the value of existing high quality feed ingredients. Our grower facilities will be located in rural agricultural communities to reduce the distance from input sourcing to end users of our products. Sanos Nutrition - from agriculture for agriculture.

As an emerging leader in the development and commercialization of energy transfer technology, SANUWAVE® presents products that help expedite wound healing on a cellular level. SANUWAVE's easy-to-use ENERGY FIRST® product portfolio works to help heal some of the most difficult, stalled, or hard-to-heal wounds by activating the body's normal regenerative process using an assortment of energy waves, from shockwaves to ultrasound. SANUWAVE values patient comfort and the importance of wound healing, recognizing its' value to not only improve patient quality of life but to help avoid further complications that could lead to amputation or even lives lost. SANUWAVE's minimally to completely non-invasive technologies can help wounds heal with little to no pain or discomfort. Most treatments can be done in under ten minutes, however, results may vary depending on wound size and patient response to treatment. The UltraMIST System delivers low-frequency ultrasound to the treatment site using a noncontact fluid (e.g., saline). MIST Systems produce a low energy ultrasound-generated mist used to promote wound healing through wound cleansing and maintenance debridement by the removal of fibrin, yellow slough, tissue exudates, and bacteria. The MOA includes control of inflammation, augmentation of local tissue perfusion, wound bacteria and bacterial biofilm reduction, increased angiogenesis, and more. The dermaPACE System is an advanced wound care device that utilizes pulsed acoustic cellular expression (PACE®) technology, a proprietary form of focused, extracorporeal shockwaves. It is the first shockwave system to be FDA-cleared for the treatment of diabetic foot ulcers (DFU). For general inquiries, please email: info@sanuwave.com

ScaleReady is a consulting company that specializes in providing strategic planning and organizational development services to help businesses scale and achieve growth.

SecondWave Systems is a pioneer in the emerging field of bio-ultrasonic medicine. The company is developing a first-of-its-kind noninvasive, wearable ultrasound stimulation platform that will give patients and their physicians a new option for treating debilitating or life-threatening disease.

ShiraTronics is a forward-thinking medtech startup committed to revolutionizing the field of migraine medicine with our minimally invasive neuromodulation system. Our mission? To transform the lives of those facing Chronic Migraine by reducing headache days and restoring quality of life.

SilkTech Biopharmaceuticals develops silk-based anti-inflammatory therapies. Our lead indication is in Dry Eye Disease, an inflammatory based chronic condition.

ABOUT SONEX HEALTH "Refined simplicity" is the guiding principle behind Sonex Health, Inc., to drive efforts and innovations that result in elegant, effective solutions to some of the healthcare system's most pressing needs. Mayo Clinic physicians Darryl Barnes, MD and Jay Smith, MD and business operations expert Aaron Keenan founded Sonex Health in 2014. Sonex Health has developed UltraGuideCTR™ with Meerkat Technology™ to treat carpal tunnel syndrome through a less invasive approach while using real-time ultrasound guidance. Carpal Tunnel Release with UltraGuideCTR and real-time ultrasound guidance allows a procedure that once took place in an operating room to be safely and effectively performed in a surgery center or office setting, resulting in rapid patient recovery, improved cosmesis, and reduced costs. ABOUT UltraGuideCTR The low profile UltraGuideCTR™ with Meerkat Technology™ enables physicians to perform Carpal Tunnel Release surgery through a small wrist incision under real-time ultrasound guidance. CTR with ultrasound guidance relieves the symptoms of carpal tunnel syndrome while minimizing recovery time. Most patients can return to work and the activities in 3-6 days while enjoying immediate motion so they can focus on getting back to their lives and the activities they love. ABOUT UltraGuideTFR Performing trigger finger release with UltraGuideTFR and real-time ultrasound guidance allows for concurrent visualization of the internal structures of the palm and fingers. The ability to identify key anatomical landmarks via ultrasound supports a safe and successful transection of the pulley through a single small incision.

Spineology's OptiMesh is the only conforming, patient specific lumbar expandable implant on the market. OptiMesh is delivered through the smallest insertion profile, dynamically conforms to a patient’s unique endplate morphology, and powerfully expands to one of the largest implant footprints available. Spineology’s OptiMesh features our unique Conform and Expand™ technology, enabling a custom anatomical fit for lumbar fusion surgical patients. OptiMesh is designed to overcome the challenges of static and mechanically expandable implants.

SpineThera designs and develops sustained-release, injectable drugs to meet the unique safety requirements for administration in and near the spine. Our proprietary drugs offer patients and physicians new treatment options that reduce risk, improve outcomes, and manage overall treatment costs in markets with few or no approved drugs.

SpineThera designs and develops sustained-release, injectable drugs to meet the unique safety requirements for administration in and near the spine. Our proprietary drugs offer patients and physicians new treatment options that reduce risk, improve outcomes, and manage overall treatment costs in markets with few or no approved drugs.

Starkey is a privately held, global hearing technology company headquartered in Eden Prairie, Minnesota, USA. We are recognized for our innovative design, development and distribution of comprehensive digital hearing systems. We develop products using an evidence-based design approach, meaning that rigorous testing takes place to prove the benefits of a new technology or algorithm before a hearing aid is ever fit on a patient. Every Starkey employee is committed to helping people on their journey to better hearing every day. Starkey operates 25+ facilities and conducts business in more than 100 markets worldwide. We develop, manufacture and distribute hearing aids via three distinct brands - Audibel, NuEar and our original brand, Starkey. Learn more about us on our blog: www.starkey.com/blog

Stimdia Medical, Inc., is a privately held company headquartered in Minneapolis, MN and has developed the pdSTIMTM System, a minimally invasive, temporary, neuromuscular stimulation system which has received FDA Breakthrough Device Designation. Mechanical ventilation (MV) is considered to be a lifesaving treatment in patients suffering respiratory failure to achieve sufficient pulmonary gas exchange. However, prolonged MV can promote atrophy and contractile dysfunction of the primary muscle utilized in respiration, the diaphragm. Significant loss in muscle mass results in a reduction in diaphragmatic function and compromises the ability of patients to breath on their own. The pdSTIM System was designed to awaken and restore the integrity of the diaphragm muscle in patients who are on MV. This is accomplished with the use of subcutaneously inserted temporary leads connected to the pdSTIM console and utilizes the proprietary RespiSyncTM sensing and stimulation algorithms to coordinate phrenic nerve stimulation with physiologic diaphragmatic movement in synchrony with mechanical ventilators. The pdSTIM System has not yet received regulatory clearances or approvals and is not currently for sale in any country.

STI has been a pioneer in medical contracting since 1981. Today, we continue as a leader, expanding our resources to better serve you, our customer. From the initial contact to the final development of your product, we enforce rigid, industry leading standards. This commitment has earned STI an international reputation for dependable contract packaging, responsive service, and the ability to adapt to the ever-changing needs of the healthcare industry. Our STI team specializes in LEAN manufacturing which results in increased capacity, cost savings and work cell efficiency.

Surmodics is the global leader in surface modification technologies for intravascular medical devices and a leading provider of chemical components for in vitro diagnostic (IVD) immunoassay tests and microarrays. Surmodics is pursuing highly differentiated medical devices that are designed to address unmet clinical needs and engineered to the most demanding requirements.

CAUTION -– Investigational device. Limited by Federal (or United States) law to investigational use. SynerFuse is long-term pain management without the use of addictive opioids. SynerFuse combines two FDA-approved technologies and synergistically fuses both in order to attack the problem of long-term, post-surgery, lower back pain, with a preemptive, drug-free pain management system.

Syntiron LLC, is dedicated to developing innovative vaccines for humans. Our patented microbial antigen discovery and purification technology targets proteins that acquire iron, a critical nutrient that is required for survival of the bacteria. These proteins are expressed on the cell surface and are similar among different strains, making them ideal vaccine antigens. Our proprietary platform enables rapid identification of these proteins, which can then be directly extracted from the host cell or produced recombinantly for preclinical vaccine development.

Tychon Biosciences is a biotechnology company commercializing novel technology in the rapidly expanding Immuno-oncology marketplace that offers similar high-specificity cancer killing relative to recently-approved cancer therapies, yet with increased safety and decreased cost. Using Tychon’s BiND platform, a first-in-class bi-specific nanoring platform as an immediate therapy that targets both an antigen receptor on a cancer cell, and T-cell—binding them together and allowing your T-cells to attack cancer cells naturally without the need for genetic engineering.

At Valerian Materials we are creating a better planet through the delivery of a versatile, bio-based monomer, called Nuvone, to polymer products that in turn can be recycled, composted, and simply regenerated back to the original monomer-state for use over and over again.

Valley Tissue Culture is a seed potato company that usesmicropropagation in a sterile laboratory to produce potato seeds.

Vascudyne Inc is a biotechnology company based in Minnesota, focused on regenerative medicine through engineered biological tissues. Founded in 2014 and headquartered in Stillwater, with operations in Saint Paul, Vascudyne develops acellular in-vitro grown allograft tissues that mimic the properties of natural human tissue. The company’s TRUE™ Tissue Technology is a proprietary platform that produces 100% biological soft tissue implants. Their product portfolio includes the TRUE™ Graft for vascular access in hemodialysis, the TRUE™ Valve for engineered valved conduits, and the TRUE™ Patch for tissue repair. Vascudyne emphasizes the use of biologically derived extracellular matrix materials and tunable anisotropic tensile properties in their manufacturing processes. Vascudyne has achieved significant milestones, including successful First-in-Human studies for the TRUE™ Graft and preclinical validations for their products. The company operates within Minnesota’s "Medical Alley," benefiting from the region's medtech ecosystem, and has raised a total of $19.63 million in funding to support its innovative work in regenerative biomaterials.

Vireo was founded as a pioneer in medical cannabis in 2014 and is fueled by an entrepreneurial drive. Vireo subsidiary companies cultivate and manufacture a wide variety of high-quality cannabis strains and products for sale through wholly-owned retail dispensaries and licensed third-party dispensaries, with a relentless focus on delighting customers and serving the communities in which we live and operate.

Founded in 2015, Visura is a medical device company dedicated to delivering state-of-art visualization solutions to improve the quality of transesophageal echocardiogram probe intubations. Visura has developed the TEECAD System, the world's first, FDA-cleared, disposable camera that seamlessly connects to a TEE probe, providing physicians real-time visualization for more efficient and effective probe placement.

Vyriad is a biotechnology company that develops targeted genetic therapies using engineered viruses and viral vectors for oncolytic virotherapy and gene editing applications.

GOAL: DISPRUPT AND TAKE OVER AN OLD AND OVERLOOKED $150 MILLION/YR. MARKET BY LEVERAGING OUR SUPERIOR AND CLINICALLY PROVEN DEVICE DESIGN WHY IS IT POSSIBLE? Current oral airways have been continually proven to be defective and studies have proven that these common airways are not adequate to maintain the oropharynx airway. Further, they are not designed to control the ever-problematic tongue. Even more, our studies showed that current oral airways possess no proportional dimensional standards in relation to how it would impact the oropharyngeal area. THE PROBLEM The biggest impediment, after placement of an oral airway, is the relaxation of the soft tissue structures in the hypopharynx. These structures are inclined to collapse, thus obstructing airflow, while occurring from both front-to-back and side-to-side, thus greatly decreasing the size of the oral opening. In relation, literally every patient before and after anesthesia, CPR, or sedation, is provided with a manual jaw-thrust to prevent the tongue from falling back and obstructing the airway. Furthermore, almost every patient intubated is provided with an airway to prevent biting of the soft endotracheal tube. Both of these procedures involve manually protracting the lower jaw by pulling it forward relative to the upper jaw. SOLUTION Studies have proven that mandibular advancement increases the oropharynx opening under anesthesia, but nobody designed that embodiment into an oral airway, or thought to design an airway to also control the tongue…until now. INTRODUCING OUR LOWER-JAW THRUST (LJT) ORAL AIRWAYS WHICH ARE ENGINEERED TO INCREASE THE OPENING OF THE OROPHARYNX AIRWAY & CONTROL THE TONGUE

Wilson Wolf Manufacturing invents, designs, and manufactures innovative cell culture devices and associated ancillary products. Our mission is to create hope for cancer patients, one device at a time. G-Rex® bioreactors, our flagship product line, are uniquely suited for the rapid expansion of immune cell types for academic research and commercial cell therapy manufacturing. We focus on the revolutionary field of T cell therapy, which is generating impressive clinical outcomes for once incurable cancer types. Wilson Wolf has partnered with Fresenius Kabi and Bio-Techne to form ScaleReady, a marketing, technical support, and commercialization organization focused on providing the most scalable cell therapy manufacturing platform in the industry. The spirit of the partnership and the ScaleReady business allows us to simplify T cell manufacturing by offering the most innovative solutions in the industry, both immediately and into the future, through collaborative development of new products that address the challenges of scaling a cell therapy. Contact us with questions or to learn how our expertise in the field of T cell therapy manufacturing can help your organization develop commercially viable, highly reliable and repeatable manufacturing processes.

ZOLL Medical is a medical devices company that specializes in healthcare technology for emergency response, with a focus on cardiac care and resuscitation.