List of Biotech, Pharmaceutical & Life Sciences companies in Michigan - 73

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AirLife

AirLife

2710 Northridge Dr NW, Grand Rapids, Michigan 49544, US

AirLife is the global leader in consumable breathing products, specializing in respiratory care, anesthesia, and patient monitoring solutions. AirLife has brought together the most trusted brands in anesthesia and respiratory care, such as SunMed, Salter Labs, Ventlab, Ethox Medical, Westmed, Vital Signs and Ballard. Our family of brands offers a product portfolio that spans the continuum of care from first responder to home care, with safety, patient comfort, and clinical performance in mind.

Akadeum Life Sciences

Akadeum Life Sciences

Ann Arbor, Michigan, US

Akadeum Life Sciences® has developed a next generation platform that solves long-standing problems across cell therapy and other research, diagnostic and therapeutic markets. The proprietary buoyant microbubble technology platform addresses the need for high cell quality, scalability, time and workflow that current magnetic particle-based products commonly used in cell therapy manufacturing and research can’t address. The Company has several GMP grade and Clinical Ready kits to enable each stage of cell therapy manufacturers pipeline. Harnessing the microbubble capability, the Alerion™ Microbubble Cell Separation System enables cell isolation from tens of billions of cells in apheresis material in under an hour, significantly expanding capacity of manufacturers. Akadeum is currently working with some of the largest corporations and forward-thinking leaders in the industry. The power of the Akadeum microbubble platform is an elegant and easy-to-use technology that can enable faster, more accurate, and scalable workflows to improve human health. Better Isolations. Healthier Cells.

Ambient Biosciences

Ambient Biosciences

Ann Arbor, Michigan, United States

At Ambient Biosciences, we are dedicated to being a true partner in your success. We bring the same spirit of versatility, transparency, and innovation to our customer relationships as we do to our technology. Our approach is to take the mystery out of biomolecule stabilization, making it an accessible and collaborative process that empowers you to feel confident about your products and assays.

Anchor Balloon

Anchor Balloon

7462 Oak Shore Dr

Novel Angioplasty Balloon with Guidewire Anchoring Technology that Enables Device Advancement Interventional Cardiology Neurointervention Interventional Radiology Endovascular Interventions

Arbor Assays

Arbor Assays

Ann Arbor, Michigan, United States

Arbor Assays is the first employee-owned life sciences company and is dedicated to advancing scientific discovery by providing innovative and reliable assay solutions. Our mission is to equip researchers and scientists worldwide with high-quality scientific tools and support their objectives with unparalleled customer service. Arbor Assays strives to be a trusted partner to our customers through our commitment to quality, integrity, and collaboration. As employee-owners, we are driven not by investor demand, but rather by a shared sense of responsibility to each other, our customers, our community, and our planet.

Autocam Medical

Autocam Medical

4152 East Paris Ave SE, Kentwood, MI 49512, US

Autocam Medical is a precision-machining contract manufacturer of highly engineered implants and instruments for surgical applications. Our product specialties include custom bone screws, bone plates and fixation devices; and perfect-fit complementary, surgical drivers, drill bits, taps and other rotary cutting instruments. We have decades of experience in every aspect of medical machining manufacturing, with specialties in CNC milling, turning, mill/turn and cutter-grinding of all surgical-grade materials, including titanium and other high-performance specialty alloys and plastics. Autocam Medical partners with customers to provide Design for Manufacturability consultation for precision-machined components, involving our engineering team early in the planning stage adds value to the entire process. Our in-depth knowledge of how medical devices work and interact gives customers an added competitive advantage.

BAMF Health

BAMF Health

Doug Meijer Medical Innovation Building, Medical Mile

BAMF Health is the world's first vertically integrated platform for molecular imaging and radiopharmaceutical therapy. Using the most advanced imaging and therapy technologies, BAMF Health is dedicated to providing comprehensive and intelligent treatment options for patients with serious health issues such as cancer, heart disease, and stroke.

Becker Orthopedic

Becker Orthopedic

Troy, Michigan, United States

Becker Orthopedic was founded in 1933 by Otto K. Becker to provide high quality orthotic components and central fabrication services. Today, Becker Orthopedic remains a family business dedicated to quality, service, and innovation in the field of orthotics.

Biocrede

Biocrede

Plymouth, Michigan, United States

Biocrede is a biomedical technology company that develops innovative biomed-tech solutions to restore health, extend life, and reduce hospitalization length for patients worldwide.

BlueWillow Biologics

BlueWillow Biologics

Ann Arbor, Michigan, United States

BlueWillow Biologics® is developing and enabling a new generation of safe and effective nasal vaccines to protect global populations from respiratory infections, sexually transmitted diseases, and food allergies. Our novel intranasal NanoVax® adjuvant platform activates mucosal immunity, the body’s first line of defense, while also inducing systemic immunity. We are a clinical-stage company advancing a pipeline of proprietary programs including Peanut Allergy, HSV-2, Covid-19, Anthrax, Pandemic Flu and RSV.

Bryllan

Bryllan

Brighton, Michigan, United States

Bryllan is a contract manufacturing company that specializes in producing potent and cytotoxic compounds meeting US FDA and global regulatory standards.

CircNova

CircNova

Detroit, Michigan, United States

CircNova, Inc. is a biotechnology company that leverages our unique AI NovaEngine™ to generate, analyze and identify circular RNA for therapeutic development.

Corium

Corium

Grand Rapids, Michigan, United States

Corium is a commercial-stage biopharmaceutical company that is leading the development and commercialization of central nervous system (CNS) healthcare therapies that provide clinicians with important treatment options for patients, their families, and their caregivers. Collaborating with some of the world's largest pharmaceutical and consumer product companies, we have a track record and depth of experience in taking products from concept, through development, to manufacturing and final commercialization.

Daicel Arbor Biosciences

Daicel Arbor Biosciences

Ann Arbor, Michigan, United States

Daicel Arbor Biosciences is a development and manufacturing company founded by scientists to serve our peers in molecular biology applications. We are a passionate organization of scientists determined to deliver cost-effective, user-friendly products to researchers of genetics and synthetic biology. The Daicel Arbor Biosciences team prides itself on providing exceptional customer service and timely technical support to new or advanced users on our array of products. We routinely collaborate with our customers and research partners to develop innovative solutions to address their unique applications. From discussing the feasibility of a project to providing fast, reliable laboratory services, we are here to help.

Delphinus Medical Technologies, Inc.

Delphinus Medical Technologies, Inc.

Novi, Michigan, United States

Delphinus Medical Technologies, Inc. is an innovation leader in advanced ultrasound development, introducing a dynamic new technique to image the breast with the use of sound and water. Headquartered in Novi, MI, Delphinus is the first company to design and manufacture a whole breast ultrasound system that utilizes a ring transducer to transmit and receive ultrasound signals. Called SoftVue™, and featuring proprietary TriAD™ (triple acoustic detection) technology, the system captures reflection echoes from all directions around the breast and gathers transmitted signals coming through the breast. This is something no other ultrasound system, currently available, can do. SoftVue has received 510(k) clearance from the U.S. Food and Drug Administration for diagnostic imaging purposes and is not intended for use as a replacement for screening mammography. Formed in 2010 as a spin-out of Karmanos Cancer Institute in Detroit, MI, Delphinus is committed to creating improved imaging methods that assist medical professionals better define and diagnose breast disease, while establishing a better patient experience that can be available for all women, regardless of age, and without concern of radiation or discomfort.

Detroit R&D

Detroit R&D

Detroit, Michigan, United States

Detroit R&D is a biotechnology company that specializes in manufacturing ELISA, antibodies, and assay kits.

Diapin Therapeutics

Diapin Therapeutics

Northville, Michigan, United States

Diapin Therapeutics is a clinical-stage drug development company developing novel therapeutics for the treatment of cardiovascular and metabolic diseases. The company is focused on peptide-based therapies for diabetes and has announced groundbreaking results from the latest study of their compound DT-109, a novel oral tripeptide that inhibits NASH progression in non-human primates. Diapin Therapeutics is also known for its tripeptide Diapin, which effectively lowers blood glucose levels in male patients. The company has an option agreement with the University of Michigan to commercialize peptide-based therapies for cardiovascular and metabolic diseases.

DNA Software

DNA Software

Ann Arbor, Michigan, United States

DNA Software is the preferred partner to solve your diagnostic design and analysis problems.Our customized software platform predicts the “sweet spots” in the target and designs with optimum sensitivity and specificity. DNA Software provides diagnostic solutions to our partners saving time, money and resources, including difficult multiplex panel design for the most challenging targets.

Ecovia Renewables

Ecovia Renewables

Ann Arbor, Michigan, United States

Ecovia Renewables Inc. was formed in 2014 as a spin-out company from the University of Michigan. It is our mission to develop and commercialize high-performing biobased ingredients and materials from sustainable processes at the best value for our customers. We do this by having microbial ecosystems work for us. Our suite of Ecovia™ Biopolymers are created from a proprietary fermentation process. They are affordable, biobased, biodegradable, and functional alternatives to conventional acrylate and acrylamide polymers and starch-based biopolymers. Applications range from soil additives for water retention to super-absorbent cores for infant diapers to thickeners for personal care and industrial products, among many others.

ENDRA Life Sciences

ENDRA Life Sciences

Ann Arbor, Michigan, United States

ENDRA Life Sciences Inc. ("ENDRA"​) (NASDAQ: NDRA) is a developer of enhanced ultrasound technologies. ENDRA is developing a next generation Thermo-Acoustic Enhanced UltraSound (TAEUS™) platform to enable clinicians to visualize human tissue composition, function and temperature in ways previously possible only with CT & MRI - at a fraction of the cost, and at the point-of-care. ENDRA's first TAEUS application will focus on the quantification of fat in the liver, for early detection and monitoring of Non-Alcoholic Fatty Liver Disease (NAFLD). ENDRA's goal is to bring new capabilities to ultrasound - thereby broadening access to better healthcare. For more information, please visit www.endrainc.com. Non-Alcoholic Fatty Liver Disease (NAFLD) is a condition closely associated with obesity, diabetes, hepatitis-C and certain genetic predispositions in which fat accumulates in the liver. NAFLD affects over 1 billion people globally and is estimated to cost the U.S healthcare system over $100B annually. NAFLD is often asymptomatic and, If left untreated, NAFLD can progress to inflammation (NASH), tissue scarring (fibrosis), cell death (cirrhosis) and liver cancer. By 2025, NAFLD is forecast to be the greatest root cause of liver transplants. The only tools currently available for diagnosing and monitoring NAFLD are impractical: expensive Magnetic Resonance Imaging (MRI) or an invasive surgical biopsy.

Endress+Hauser Optical Analysis

Endress+Hauser Optical Analysis

Ann Arbor, Michigan, United States

Endress+Hauser is a global leader in measurement and automation technology for process and laboratory applications. The family company, headquartered in Reinach, Switzerland, achieved net sales of approximately 3.7 billion euros in 2023 with a total workforce of more than 16,500. Endress+Hauser devices, solutions and services are at home in many industries. Customers thus use them to gain valuable knowledge from their applications. This enables them to improve their products, work economically and at the same time protect people and the environment. Endress+Hauser is a reliable partner worldwide. Its own sales companies in more than 50 countries as well as representatives in another 70 countries ensure competent support. Production facilities on four continents manufacture quickly and flexibly to the highest quality standards. Endress+Hauser was founded in 1953 by Georg H Endress and Ludwig Hauser. Ever since, the company has been pushing ahead with the development and use of innovative technologies, now helping to shape the industry's digital transformation. 8,900 patents and applications protect the Group's intellectual property. For further information, please visit www.endress.com/media-center or www.endress.com

Esperion

Esperion

Ann Arbor, Michigan, United States of America

Official LinkedIn page for Esperion. At Esperion, we discover, develop, and commercialize innovative medicines to help improve outcomes for patients with or at risk for cardiovascular and cardiometabolic diseases. The status quo is not meeting the health needs of millions of people with high cholesterol – that is why our team of passionate industry leaders is breaking through the barriers that prevent patients from reaching their goals. Providers are moving toward reducing LDL-cholesterol levels as low as possible, as soon as possible; we provide the next steps to help get patients there. Because when it comes to high cholesterol, getting to goal is not optional. It is our life’s work. For more information, visit esperion.com and esperionscience.com and follow us on X at twitter.com/EsperionInc. Community guidelines: https://bit.ly/3vLCGdO Certified Great Place To Work®

ETEC

ETEC

Dearborn, Michigan, United States

Desktop Metal (NYSE:DM) is driving Additive Manufacturing 2.0, a new era of on-demand, digital mass production of industrial, medical, and consumer products. Our innovative 3D printers, materials, and software deliver the speed, cost, and part quality required for this transformation. We’re the original inventors and world leaders of the 3D printing methods we believe will empower this shift, binder jetting and digital light processing. Today, our systems print metal, polymer, sand, and other ceramics, as well as foam and recycled wood. Manufacturers use our technology worldwide to save time and money, reduce waste, increase flexibility, and produce designs that solve the world’s toughest problems and enable once-impossible innovations. Learn more about Desktop Metal and our #TeamDM brands at www.desktopmetal.com.

EVOQ Therapeutics

EVOQ Therapeutics

Ann Arbor, Michigan

EVOQ Therapeutics is developing immunotherapies to improve the lives of individuals fighting autoimmune diseases. There are more than 100 chronic autoimmune diseases - many severely debilitating, and some life-threatening. According to the National Institutes of Health, up to 23.5 million Americans (over 7% of the population) suffer from autoimmune disease, and the prevalence is rising. Autoimmune disease occurs when the body’s central immune tolerance system fails - resulting in T and B cell-mediated destruction of self-tissues. This immune system failure is responsible for many devastating diseases including – Type 1 Diabetes, Celiac disease, Multiple sclerosis and Rheumatoid Arthritis. EVOQ’s technology unleashes and restores the body’s natural immune tolerance pathways.

Ferndale Pharma Group

Ferndale Pharma Group

Ferndale, Michigan, United States

Small Molecules, Contract Manufacturing

Fondazione Telethon

Fondazione Telethon

Milan, Michigan, US

Founded in 1990, Telethon Italy is one of the biggest biomedical charity in Italy, whose mission is to advance biomedical research towards the diagnosis, cure and prevention of muscular dystrophies and other human genetic diseases. Telethon Italy focuses on scientific research and does not offer healthcare, material assistance to patients and families or advocacy. Since 1991, Telethon Italy has invested 394 million Euros in research and funded 2,477 research projects on more than 445 human genetic diseases, which range from basic research to clinical trials.

Functional Fluidics

Functional Fluidics

Detroit, Michigan, US

Functional Fluidics is a healthcare company that provides a testing platform to assess the health of red blood cells, crucial for oxygen delivery to organs.

Gene Codes

Gene Codes

Ann Arbor, Michigan, United States

Gene Codes Corporation is an international software firm specializing in bioinformatics software for DNA sequence analysis. Gene Codes'​ scientist-friendly software tools hold the dominant share in the DNA sequencing sector and are unrivaled in forensic DNA identification for mass fatalities. Gene Codes'​ success is built on customer-driven product development, combining the latest programming techniques, rigorous quality control and an open dialogue with customers to produce products of the utmost usability and industry relevance. Since 1991, when Gene Codes first introduced its groundbreaking Sequencher software for sequence analysis, we have served the needs of industrial, academic and government-based biotechnology groups across the globe. As the popularity of Sequencher has grown, so has the company. Gene Codes is a motivated, enthusiastic, high-energy organization based in Ann Arbor, with offices in New York City and in Brighton, England. Gene Codes'​ corporate culture values flexible collaboration, shared responsibility, and dynamic change.

Genemarkers

Genemarkers

Kalamazoo, Michigan, United States

Genemarkers is a Kalamazoo, Michigan-based contract services laboratory specializing in genomics research and molecular testing services, with a primary focus on consumer products, dermatology, skin-related research and therapeutics.. Founded in 2008 by former professor and neuroscientist Dr. Anna Langerveld, Genemarkers has proven its expertise through collaborations with cosmetic, pharmaceutical, and academic research institutions over the years. Taking pride in providing actionable, high quality data and customer service, Genemarkers' CLIA-certified and CAP-accredited laboratory has the ability to support a wide range of projects throughout discovery and development including advanced cellular models/exposures (e.g., dermal/transdermal, hepatic/extrahepatic, neuronal and bronchial/inhalation) and next generation bioinformatics and computational modeling.

Genomenon

Genomenon

Ann Arbor, Michigan, United States

Genomenon is a leading genomic intelligence company dedicated to improving the quality of patients’ lives by uncovering the genomic drivers of genetic disease and cancer. Blending the power of AI with genomic expertise, Genomenon simplifies complex genetic data into actionable insights for patient diagnosis and precision medicine development. The company’s solutions include software, data, and services. Genomenon offers advanced genomic software solutions designed to streamline and enhance genetic research and clinical decision-making. Our flagship product, the Mastermind® Genomic Intelligence Platform, provides comprehensive genomic data integration and analysis, offering researchers and clinicians a powerful tool to interpret genetic variants and their clinical relevance. Complementing this is the Clinical Knowledgebase (CKB), which focuses specifically on the landscape of somatic mutations, offering curated, actionable insights to support oncology research and personalized cancer treatment. Together, these platforms aim to accelerate discoveries and improve patient outcomes through sophisticated data analysis and knowledge integration.

Grand Rapids Community College

Grand Rapids Community College

Grand Rapids, Michigan, US

Grand Rapids Community College has been nestled in the heart of West Michigan for more than 100 years. The first community college in Michigan, GRCC was founded in 1914 to provide educational opportunities that would open doors for local citizens. That mission continues today as GRCC focuses on being relevant and responsive to its community. The GRCC Experience is seamless transfer to more than 35 college and university programs; faculty with industry practice; state-of-the-art, flexible and online learning options; honors, study away and experiential learning courses; nationally ranked sports programs, and business partnerships to develop tomorrow’s workforce. Grand Rapids Community College is West Michigan’s best choice.

HAPPE Spine

HAPPE Spine

2851 Charlevoix Dr SE, 327, Grand Rapids, Michigan 49546, US

HAPPE is an emerging leader of next generation orthopaedic and spinal implants enabled by the HAPPE™ (HydroxyApatite Porous PolyEtheretherketone) platform. The HAPPE material platform offers interconnected, cancellous porosity with exposed hydroxyapatite on pore surfaces to enable robust bone in-growth and on-growth confirmed in preclinical testing.

Hartmann's Plant Company

Hartmann's Plant Company

Lacota, Michigan, United States

The company uses tissue culture to propagatedisease free plants.

HistoSonics

HistoSonics

Ann Arbor, Michigan, United States

HistoSonics is a venture-backed medical device start-up company developing a non-invasive sonic beam therapy platform and procedure using the science of histotripsy. Histotripsy utilizes the pressure created by focused sound energy to liquify and destroy targeted tissue, including diseased tissue and tumors, at sub-cellular levels. The company's new platform delivers personalized, tissue specific treatments with precision and control, and without the undesirable side effects of many of today's interventional and surgical modalities. HistoSonics is led by a team of experienced domain experts and industry leaders with offices in Ann Arbor, Michigan and Minneapolis, MN.

Iaso Therapeutics

Iaso Therapeutics

East Lansing, MI

Iaso Therapeutics, Inc. is a start-up company spun out from Michigan State University. The company was founded in 2018 by Dr. Xuefei Huang. Dr. Huang is a MSU Foundation Professor jointly appointed in the Department of Chemistry and the Department of Biomedical Engineering, Michigan State University. In addition, he is a member of the newly formed Institute for Quantitative Health Science & Engineering. With over 25 years of experience, his research program is focused on the development of novel technologies for next generation vaccines, including vaccines targeting both cancer and infectious diseases. Iaso Therapeutics, Inc. aims to translate the cutting-edge technologies developed in the Huang laboratory to promote human health and treat diseases.

Impact Analytical

Impact Analytical

Midland, Michigan, United States

Impact Analytical is a compliance services company that specializes in analytical testing for medical devices, including material composition analysis and contaminant investigation.

Innovative BioTherapies

Innovative BioTherapies

Ann Arbor, Michigan

Innovative BioTherapies (IBT) is a small biotechnology company located in Ann Arbor, MI, focused on developing medical devices to solve unmet medical needs.

Ionetix

Ionetix

3130 Sovereign Dr., Suite 5D, Lansing, MI 48911, US

Ionetix is a Michigan-based medical device firm that designs and develops cyclotron technology-based radioisotope equipment for cancer diagnosis and therapeutic applications.

Karmanos Cancer Institute

Karmanos Cancer Institute

Detroit, Michigan, US

Karmanos Cancer Institute is a healthcare organization specializing in cancer treatment, medical services, and oncology research.

Kraig Biocraft Laboratories

Kraig Biocraft Laboratories

Ann Arbor, Michigan, United States

Kraig Biocraft Laboratories, Inc. (Trading Symbol: KBLB) is a fully reporting biotechnology company focused on the development and commercialization of spider silks. As a reporting company, our annual and quarterly reports to the SEC can be found on EDGAR and on this website. Our investments in genetic research are targeted for product development and innovative near-term solutions to meet the practical problems of our world. Our genetic engineering research has succeeded in developing what many considered to be the holy grail of material science: A practical and cost-effective technology for producing recombinant spider silk based fibers on an industrial scale. We are moving rapidly to commercialize of our spider silk technology, which we believe will have a significant impact on the global textiles industry. At the same time we are continuing to work in cooperation with leading laboratories to create new stronger and more flexible spider silk based fibers with potentially broad applications for consumers and industry in the multi-billion dollar marketplace for textiles and performance polymers. At Kraig, we are passionate about pioneering the research, development and commercialization of the next generation of high performance fibers based on genetic engineered spider silk. We are the world leader in our field of genetic research and product development.

MDI Therapeutics, Inc.

MDI Therapeutics, Inc.

46430 Peary Ct., Novi, MI 48377, US

Developing novel serpin-based therapies for the treatment of fibrosis and fibroproliferative disorders.

Michigan Technological University

Michigan Technological University

Houghton, Michigan, US

Michigan Technological University is a Higher Education institution that offers outstanding Computer Science educational programs to help students adapt to rapidly changing technologies.

Neogen

Neogen

Lansing, Michigan, United States

Neogen®'s Solutions Can Be Found at Every Step of the Food Chain. Neogen provides a comprehensive range of solutions and services for the food processing, animal protein and agriculture industries, not only helping to protect the world's food supply, but also enabling our customers to produce more efficiently and effectively than they could before. We are also proud to serve the companion and performance animal industries, as well as the fields of life sciences and toxicology.

Neurogenx Inc.

Neurogenx Inc.

314 N. Walnut Street, Suite 2A, Lansing, MI 48933, US

Our NEUROGENX Team is proud to abundantly equip and enable providers to deliver a higher standard of care to patients suffering various balance issues, neuropathy and other chronic nerve conditions. At the heart of our partnership is a philosophy in which we invest fully in our providers as partners and hold ourselves accountable and pledge our commitment. A commitment to ensure our partners both clinical and business success. We have built our NEUROGENX Solutions Program on this: (1) Support & Service (2) Performance & Results (3) Model Training & Continuous Coaching to Ensure Clinical & Business Success within the first months, throughout the first year and years to come. We recognize conscientious and enterprising providers have different needs as well as different visions about practice growth. For these reasons, we have multiple steps and pathways for procuring and implementing NEUROGENX Clinical and Business Solution Assets to create a custom fit to suit every enterprising style and budget. We're committed to work with you to customize a combination of technologies, training and support systems to attain your perfect fit!

Northern Biomedical Research

Northern Biomedical Research

Norton Shores, Michigan, US

Northern Biomedical Research is a non-clinical research organization focused on targeted delivery of therapeutics using advanced techniques. Our team is experienced in providing industry-leading research for targeted-delivery of drugs, biologics, gene/cell therapies, and medical devices. With a strong regulatory history and scientific background in neuroscience, cardiovascular research, ophthalmology, and orthopedics, our team works closely with Sponsors to design a non-clinical program to exedite the regulatory process. For more information, stop by Booth 250. Â

Northern Biomolecular Services

Northern Biomolecular Services

Kalamazoo, Michigan, US

Ocuphire Pharma

Ocuphire Pharma

37000 grand river avenue, farmington hills, mi, united states

Ocuphire Pharma Inc is a clinical-stage ophthalmic biopharmaceutical company focused on developing and commercializing innovative small molecule therapies for eye disorders. The company aims to address unmet medical needs in the ocular space, particularly in retinal and refractive disorders. Ocuphire Pharma offers research and development services to create novel treatments for various eye conditions. The company collaborates with pharmaceutical partners to advance its drug candidates through clinical trials and commercialization. Its product pipeline includes Nyxol, an ophthalmic solution for dim light and night vision disturbances; APX3330, an oral inhibitor for diabetic retinopathy and macular edema; APX2009, aimed at treating wet age-related macular degeneration; and Phentolamine Ophthalmic Solution (RYZUMVI), approved for pharmacologically induced mydriasis and under development for other conditions.

ONL Therapeutics

ONL Therapeutics

Ann Arbor, Michigan, United States

ONL Therapeutics (ONL) is a clinical-stage biopharmaceutical company committed to helping patients see the future. Our mission is to develop innovative therapeutics to protect and improve the vision of patients with a range of retinal disease and conditions. By advancing a breakthrough technology designed to prevent the death of key retinal cells caused by the activation of the natural Fas pathway, ONL is pioneering an entirely new approach to preserve sight. It is the first and only company focused on preventing Fas-mediated death of key retinal cells, which is a root cause of vision loss, a leading cause of blindness and an unaddressed medical need. ONL’s lead therapeutic candidate, ONL1204, is a first-in-class small peptide Fas inhibitor designed to protect retinal cells from both death and inflammatory signaling pathways. ONL1204 Ophthalmic Solution is being developed for the treatment of retinal detachment, an acute condition for which the company has been granted orphan drug designation by the FDA. In addition, the company is currently developing ONL1204 in geographic atrophy associated with age-related macular degeneration, glaucoma, and other acute and chronic indications.

OxUs

OxUs

Auburn Hills, Michigan, United States

Oxus is an engineering, manufacturing, and service company specializing in medical devices and gas separation technology. We design and manufacture our products in Auburn Hills, Michigan. As an ISO 13485 certified and FDA registered OEM supplier, we understand the technical challenges of product realization. We have supported our customers in bringing to market an assortment of challenging products; from industrial design and engineering, through process design and manufacturing.

Parabricks (Nvidia)

Parabricks (Nvidia)

Ann Arbor, Michigan, United States

Since its founding in 1993, NVIDIA (NASDAQ: NVDA) has been a pioneer in accelerated computing. The company’s invention of the GPU in 1999 sparked the growth of the PC gaming market, redefined computer graphics, ignited the era of modern AI and is fueling the creation of the metaverse. NVIDIA is now a full-stack computing company with data-center-scale offerings that are reshaping industry.

Penrose TherapeuTx

Penrose TherapeuTx

Plymouth, Michigan, United States

Penrose TherapeuTx is a U.S.-based pharmaceutical company focused on developing innovative small-molecule therapies for the treatment of advanced cancers. The company also develops small-molecule therapies to treat cancer and has prominent researchers and leaders in the field as part of its scientific advisory board and executive team.

Peptinovo Biopharma

Peptinovo Biopharma

600 S Wagner Road, Ann Arbor, MI, US

Chemotherapy is the foundation of cancer treatment because it is so effective, but it is also the downfall of cancer treatment because it is so toxic. Patients can experience hair loss, nausea, fatigue, aching, or neuropathy and often find that the treatment seems worse than the disease. Imagine the impact a technology would have on cancer treatment if that technology maintains or even improves the efficacy of established chemotherapies without the harmful side effects. And that is what Peptinovo aims to do. Peptinovo Biopharma Inc. has invented and patented a targeted, drug-delivery platform: Peptide-Amphiphile Lipid Micelle (PALM) that reduces or eliminates chemotherapy-induced peripheral neuropathy (CIPN), one of the most serious side effects threatening treatment outcomes for world-leading chemotherapy drugs like paclitaxel. PALM delivers higher doses of proven drugs INTO tumors, keeping them AWAY from healthy tissues. Lives are extended and side effects are avoided. Peptinovo is developing its first platform, PNB-281, to eliminate the nerve damage caused by paclitaxel against many major cancers including breast, ovarian, lung, prostate, and pancreatic cancers. Nerve damage is the most serious side-effect threatening the ability to complete the cancer treatment. Peptinovo's technology can be used to treat many cancers and it can be used with many chemotherapy drugs.

Phenomics Health

Phenomics Health

Ann Arbor, Michigan, United States

We are a bioinformatics-based precision medicine platform company translating patient-specific and population-based medical big data into novel pharmacological clinical treatment decision support products and services. We offer a proprietary technology, the PredictMed Platform, designed to help clinicians and health systems optimize precision in the selection of appropriate medications, drug combinations and dosages that improve each patient's health, while also reducing adverse reactions. Our PrecīsMed platform represents a significant step forward in accurately assessing a patient’s complete medication profile. Physicians can finally see the full spectrum of medications present in the patient, and identify appropriate dosing levels for therapeutic effectiveness. PrecīsMed can accurately assess prescribing trends, medication adherence and EHR coverage, as well as define medication concentrations in patients with comorbid disorders.

Proteos

Proteos

Kalamazoo, Michigan, United States

Proteos is committed to providing a quality foundation for drug discovery. We are a contract research organization that provides the highest quality recombinant protein expression and purification services for drug discovery research in the biotechnology and pharmaceutical industries. Our highly-skilled team of scientists utilizes diverse experience and optimized methods within a customized workflow that focuses on the end product from square one. Fully customized experimental designs allow flexibility and adaptation during the project, thus enabling data-driven decisions that lead to a higher probability of project success. Proteos is passionate about drug discovery. We know that reliable reagents are critical for the ultimate success of drug discovery programs.

Rockwell Medical

Rockwell Medical

Wixom, Michigan, United States

Rockwell Medical is a fully-integrated biopharmaceutical company targeting end-stage renal disease (ESRD) and chronic kidney disease (CKD) with innovative products and services for the treatment of iron replacement, secondary hyperparathyroidism and hemodialysis. Rockwell’s new innovative therapy Triferic is the only FDA approved drug indicated to replace iron and maintain hemoglobin in hemodialysis patients suffering from anemia. Via dialysate during each dialysis treatment, Triferic replaces the 5-7 mg iron loss that occurs in all patients, maintaining their iron balance. Unlike IV iron products, Triferic binds iron immediately and completely to transferrin (carrier of iron in the body) upon entering the blood and is then transported directly to the bone marrow to be incorporated into hemoglobin, with no increase in ferritin (stored iron and inflammation) and no anaphylaxis, addressing a significant unmet need in overcoming Functional Iron Deficiency (FID) in ESRD patients. Visit www.triferic.com to view the Triferic mode-of-action (MOA) video and for more information. Rockwell’s FDA approved generic drug Calcitriol is for treating secondary hyperparathyroidism in dialysis patients. Calcitriol (active vitamin D) injection is indicated in the management of hypocalcemia in patients undergoing chronic renal dialysis. Rockwell is also an established manufacturer and leader in delivering high-quality hemodialysis concentrates/dialysates to dialysis providers and distributors in the U.S. and abroad, with three manufacturing/distribution facilities located in the U.S. Rockwell’s products are used to maintain human life by removing toxins and replacing critical nutrients in the dialysis patient’s bloodstream. Rockwell’s exclusive renal drug therapies support disease management initiatives to improve quality of life and care of dialysis patients and are intended to deliver safe and effective therapy, while decreasing costs and improving patient convenience.

SciTech Development

SciTech Development

Grosse Pointe Farms, Michigan, United States

SciTech Development is a Specialty Pharmaceutical Company dedicated to advancing cancer treatment through safer drug delivery. They are based in Michigan, USA and are known for their innovative drug delivery platform SDP that engineers new therapeutics for better & broader clinical applications.

Seraph Biosciences, Inc

Seraph Biosciences, Inc

1001 Woodward Ave, Suite 500, Detroit, Michigan 48226, US

Seraph Biosciences, Inc. is a biomedical device company headquartered in Detroit, Michigan. The company was founded in 2014 with the primary purpose of commercializing its groundbreaking, diagnostic technology known as Seraspec®. Seraph's team consists of seasoned academic physicians, biomedical engineers, artificial intelligence experts, and device commercialization professionals tasked with combatting the major public health crises of our time. By leveraging the principles of Raman Spectroscopy, Seraspec® represents a paradigm shift away from current methods for screening and identification of dangerous bacterial, viral and fungal pathogens. Seraspec's® patented technology and method of detection effectively eliminates the need for time-consuming and costly laboratory-based methods of specimen collection, processing and pathogen identification. Safety, efficiency, accuracy and profitability are simultaneously enhanced through a portable, point-of-need technology for real-time pathogen detection and identification. A higher power just got involved in the fight against infection.

Shoulder Innovations

Shoulder Innovations

13827 Port Sheldon Road, Holland, Michigan 49424, US

The simplicity of our design--born out of our extensive experience--comes down to the basic notion that traditional fixation techniques aren't strong enough and don't last. Our InSet™ approach to Glenoid fixation is revolutionizing shoulder arthroplasty and, more importantly, improving procedure longevity--ultimately changing patient's lives.

Sling Therapeutics

Sling Therapeutics

Ann Arbor, Michigan, United States

We are a clinical-stage biopharmaceutical company developing an oral small molecule for the treatment of thyroid eye disease (TED). Our team consists of highly experienced drug developers, supplemented by global experts through our Scientific Advisory Board.

SpinTech MRI

SpinTech MRI

30200 Telegraph Rd, Bingham Farms, Michigan, US

STAGE, developed by SpinTech, is an advanced MRI imaging software platform that reduces brain scan time by 30%. The software provides enhanced visualization and quantification of scan images. STAGE automatically detects biomarkers critical to proper diagnosis of neurological conditions that cannot be seen with current MRI techniques (i.e. traumatic brain injury, dementia, Parkinson's, Multiple Sclerosis, and stroke). We're committed to bringing the future of imaging technology to every patient suffering from neurological disease with a cost effective, workflow-efficient software platform that improves patient outcomes and maximizes costly imaging equipment ROI. STAGE software is compatible with most manufacturers' existing equipment. Visit our website to learn more and set up a demo!

Strata Oncology

Strata Oncology

ANN ARBOR, Michigan, United States

Strata Oncology is a high-growth, state-of-the art, precision oncology company, delivering a new standard of care that integrates molecular profiling, decision support and clinical trial participation into routine practice. We do this by partnering with major healthcare systems across the country, who systematically send their cancer patients’ biopsies to our high-throughput CLIA lab for genomic sequencing, with results provided to the oncologist within days, indicating the tumor profile, and matches to appropriate therapies and drug trials. This accelerates the move to personalized medicine – right medicines to the right patients at the right time. Our personnel are passionate about and committed to making a positive difference, now, in the lives of cancer patients and their families. Clinicians, pathologists, bioinformaticists, software engineers, lab technicians and more, coming together to give access to those without, uncovering insight that might be hidden, all while spreading urgency to all. Experience a career that connects a fast-paced team environment with a worthy pursuit – feel good about what you’ve accomplished at the end of every day!

Sub Terra (Prairie Plant Systems)

Sub Terra (Prairie Plant Systems)

White Pine, Michigan, United States

Underground API-Bearing Plants

Telocyte

Telocyte

Grand Rapids, Michigan, United States

We are a biotechnology company dedicated to curing Alzheimer's disease. We are planning FDA-sponsored human trials, using telomerase therapy to reset cell aging within the central nervous system. We believe that Alzheimer's disease can stopped, prevented, and cured.

Terumo Medical

Terumo Medical

Ann Arbor, Michigan, United States

ADVANCING HEALTHCARE WITH HEART CREATE YOUR FUTURE, AND OURS Here you grow your own way, you create to innovate, and learn as you go, alongside like minds who share the same commitment to the future of healthcare. We are proud to have launched global development programs to help our associates shape their careers alongside the future of healthcare. ENJOY A REWARDING AND MEANINGFUL CAREER As a team, we make a real difference to the health and wellbeing of our patients today, and leave a lasting legacy for tomorrow. Your time is dedicated to innovation, problem solving, teamwork and lifelong learning, as an integral part of our ever-curious, always committed, continually collaborative environment. We foster a growth mindset culture, embracing mistakes as an opportunity to learn, and celebrating the small wins along the way, so we can all grow together. FOR TERUMO, FOR EVERYONE, EVERYWHERE Whatever you do – marketing, engineering, sales or manufacturing – our teams look out for one another, respect and support each other in achieving our goals, and we value diversity and inclusion, empowering everyone to bring their authentic self to work. If you’re ready to advance healthcare with heart, we look forward to hearing from you.

Tetra Therapeutics

Tetra Therapeutics

Kalamazoo, Michigan, United States

Tetra Therapeutics is a clinical stage biotechnology company developing a portfolio of therapeutic products. Tetra designs drugs to treat memory loss and cognitive impairment by improving how the brain processes and stores information. The company is focused on treating cognitive impairment and memory loss by improving brain function.

Thompson Retractor

Thompson Retractor

10170 E Cherry Bend Rd, Traverse City, Michigan 49684-6843, US

Thompson Surgical Instruments, also known as Thompson Retractor, is a prominent manufacturer of surgical retractors. Founded by Dr. Richard C. Thompson in 1965, the company began with a patented table-mounted retractor and has since evolved under the leadership of Dan Farley, who established the company in 1983. The company specializes in designing and manufacturing table-mounted retractors that provide stable and controlled exposure during surgical procedures. These retractors enhance surgical efficiency and safety by allowing for hands-free operation. Thompson Surgical Instruments offers customizable systems tailored to various surgical needs, with all products proudly made in Michigan, USA. The company is recognized globally for its commitment to quality and customer service, providing support through multiple channels. Additionally, Thompson Surgical Instruments contributes to the community by donating a portion of its profits to charitable organizations across the United States.

Tissue Regeneration Systems

Tissue Regeneration Systems

Plymouth, Michigan, United States

Tissue Regeneration Systems™ (TRS™) is a start-up medical device company commercializing a breakthrough skeletal reconstruction and bone regeneration technology platform licensed from the Universities of Michigan and Wisconsin. Our technology addresses a broad range of clinical applications, and has been validated by comprehensive University, NIH and company-sponsored research initiatives spanning a period of well over a decade. NOVEL 3D PRINTED RESORBABLE SCAFFOLDS TRS has a proven capability to fabricate complex, patient specific, load- bearing resorbable implant solutions using 3D printing methods. UNIQUE BIOACTIVE MINERAL COATING Our proprietary mineral coating, Affinity™, exhibits unique bioactive properties that can be applied to our resorbable scaffolds, as well as to conventional orthopedic and spine implants. The Affinity morphology is a plate-like nanostructure, which mimics the mineral structure of native bone, and modulates the biologic environment in a manner not previously exhibited by other implant coatings. SCALABLE FDA COMPLIANT MANUFACTURING TRS has established a fully independent, FDA-compliant manufacturing facility with a certified cleanroom. Our operation can support commercial product volumes. FDA CLEARANCE Both our 3D printed resorbable scaffold technology and our Affinity mineral coating have received FDA 510(k) clearance. STRONG INTELLECTUAL PROPERTY AND TRADE SECRET POSITION TRS has an extensive patent portfolio and has also accumulated a number of important trade secrets in perfecting our technology and fabrication methods. Together, this creates meaningful protection and exclusivity for our technology platform.

TSRL Inc

TSRL Inc

Ann Arbor, Michigan, United States

Therapeutic Systems Research Laboratories (TSRL), Inc. is a privately women-owned, pre-clinical accelerator based in Ann Arbor, Michigan focused on building companies that develop infectious disease therapeutics. A key aspect of our strategy is our Technology Accelerator, an ongoing collaborative process that lends our expertise and capabilities to entrepreneurs seeking to obtain the data and non-dilutive funding necessary to develop and/or commercialize their inventions. One focus is improving existing drug products by applying our versatile prodrug platform technologies to optimize therapy regimen for treating infectious diseases. Potential target indications include: influenza, HSV, VZV, CMV, EBV, poxvirus, HPV, Adenovirus, and RNA viruses. We currently employ ten full-time employees and a number of drug development consultants and generate annual revenues of approximately $2M from royalties and grants. Our team has broad experience in chemistry, molecular biology, biochemistry, analytical chemistry, in vivo animal model, PK/ADME, toxicology and formulation. Our research is conducted in a 7,200 sq. ft. facility of which 5,000 sq. ft. is wet lab space, with on-site analytical chemistry, formulation, cell culture equipment and in vivo testing capabilities.

Vantis Vascular, Inc.

Vantis Vascular, Inc.

Headquarters Address Not Available

Vantis Vascular is a performance-driven technology company that aims to provide faster, easier, and safer vascular interventions. Their technology is focused on making structural, peripheral, and coronary treatments safer.

Vestaron

Vestaron

Kalamazoo, Michigan, United States

Vestaron Crop Protection is an ag technology company dedicated to providing our customers with the powerful solutions they need to meet the growing challenges of modern agriculture. Founded in 2005 and headquartered in Durham, NC (USA), we are producing a pipeline of powerful insecticides with new modes of action based on peptides modified from the venom of spiders and other venomous animals. Naturally soft on pollinators, beneficials, and local biodiversity, our innovations have earned recognition from the Crop Science Awards and the EPA’s Green Chemistry Challenge. In 2024, we became the first agriculture and food company inducted into the Global CleanTech 100 Hall of Fame. Our first product, SPEAR® LEP, is proven on more than 650,000+ acres and continues to gain market share in North America. Recently, SPEAR LEP has been approved for Emergency Use Authorization in several EU countries as a desperately needed solution to help farmers combat the destructive impact of tomato leafminer (Tuta absoluta) infestations which cause substantial yield and economic losses for farmers across the Mediterranean region of Europe. In 2024 the Environmental Protection Agency (EPA) approved our second novel-acting insecticide, BASIN®. Vestaron Crop Protection: Unconventional, by nature.

Wayne State University

Wayne State University

Detroit, Michigan, US

Wayne State University is a Higher Education institution that offers a wide range of academic programs and conducts research.

Zivo Bioscience

Zivo Bioscience

Keego Harbor, Michigan, United States

OTCQB: ZIVO. ZIVO Bioscience, Inc., is a research and development company with an intellectual property portfolio comprised of proprietary algal and bacterial strains, biologically active molecules and complexes, production techniques, cultivation techniques and patented or patent pending inventions for applications in human and animal health. Please visit www.zivobioscience.com for more information.

Zomedica

Zomedica

Ann Arbor, Michigan, United States

Zomedica is a veterinary pharmaceutical and health care solutions company creating innovative products for companion animals (canine, feline and equine).